Table 1.
Gene ontology enrichment in cluster 4
GO.IDTermAnnotatedP-value (weight Fisher’s)Genes contributing to enrichment
GO:0010758 Regulation of macrophage chemotaxis 0.00355 C5ar1, Ccl2, Mmp28, Ptk2b, Rarres2 
GO:0098542 Defense response to other organism 62 0.00776 C5ar1, Cxcl1, Ddx60, Epx, Fgr, Gbp2, Iigp1, Il27ra, Irf5, Isg15, Lyz1, Mpo, Mx2, Naip6, Nlrc4, Oasl2, Oprk1, Spn, Spon2, Syk 
GO:0032649 Regulation of IFN-γ production 10 0.02583 Fzd5, Il27ra, Isg15, Isl1, Runx1 
GO:0060638 Mesenchymal-epithelial cell signaling 0.00537 Fgf10, Hgf, Tnc, Wnt2b 
GO:0001706 Endoderm formation 14 0.00829 Dusp1, Gata4, Gata6, Inhba, Nanog, Nog, Pou5f1 
GO:0045766 Positive regulation of angiogenesis 32 0.01032 Angpt2, C5ar1, Ccbe1, Ctsh, Gata4, Gata6, Hgf, Isl1, Prkcb, Ptk2b, Runx1, Srpx2 
GO:0043534 Blood vessel endothelial cell migration 13 0.02281 Angpt2, Egr3, Klf4, Nr4a1, Ptk2b, Srpx2 
GO:0030510 Regulation of BMP signaling pathway 30 0.01664 Bmper, Cav1, Chrdl2, Crb2, Fstl3, Gata4, Gata6, Gdf3, Kcp, Nanog, Nog 
GO:0071371 Cellular response to gonadotropin stimulation 0.00222 Egr2, Egr3, Egr4, Gata4, Gata6, Inhba 
GO:0019827 Stem cell maintenance 30 0.01664 Dppa2, Esrrb, Fgf10, Klf4, Nanog, Nog, Phf19, Piwil2, Pou5f1, Prdm14, Tcl1 
GO:0008584 Male gonad development 26 0.02506 Esr2, Fgf9, Gata4, Inhba, Lhx9, Nupr1, Rxfp2, Tcf21, Tex19.1, Zfpm2 
GO.IDTermAnnotatedP-value (weight Fisher’s)Genes contributing to enrichment
GO:0010758 Regulation of macrophage chemotaxis 0.00355 C5ar1, Ccl2, Mmp28, Ptk2b, Rarres2 
GO:0098542 Defense response to other organism 62 0.00776 C5ar1, Cxcl1, Ddx60, Epx, Fgr, Gbp2, Iigp1, Il27ra, Irf5, Isg15, Lyz1, Mpo, Mx2, Naip6, Nlrc4, Oasl2, Oprk1, Spn, Spon2, Syk 
GO:0032649 Regulation of IFN-γ production 10 0.02583 Fzd5, Il27ra, Isg15, Isl1, Runx1 
GO:0060638 Mesenchymal-epithelial cell signaling 0.00537 Fgf10, Hgf, Tnc, Wnt2b 
GO:0001706 Endoderm formation 14 0.00829 Dusp1, Gata4, Gata6, Inhba, Nanog, Nog, Pou5f1 
GO:0045766 Positive regulation of angiogenesis 32 0.01032 Angpt2, C5ar1, Ccbe1, Ctsh, Gata4, Gata6, Hgf, Isl1, Prkcb, Ptk2b, Runx1, Srpx2 
GO:0043534 Blood vessel endothelial cell migration 13 0.02281 Angpt2, Egr3, Klf4, Nr4a1, Ptk2b, Srpx2 
GO:0030510 Regulation of BMP signaling pathway 30 0.01664 Bmper, Cav1, Chrdl2, Crb2, Fstl3, Gata4, Gata6, Gdf3, Kcp, Nanog, Nog 
GO:0071371 Cellular response to gonadotropin stimulation 0.00222 Egr2, Egr3, Egr4, Gata4, Gata6, Inhba 
GO:0019827 Stem cell maintenance 30 0.01664 Dppa2, Esrrb, Fgf10, Klf4, Nanog, Nog, Phf19, Piwil2, Pou5f1, Prdm14, Tcl1 
GO:0008584 Male gonad development 26 0.02506 Esr2, Fgf9, Gata4, Inhba, Lhx9, Nupr1, Rxfp2, Tcf21, Tex19.1, Zfpm2 

Selected gene ontologies that are significantly enriched in cluster 4 by weighted Fisher's test (P < 0.05) and the genes that contribute to this enrichment.

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