Table 1. Comparison of... | Rockefeller University Press

Table 1.

Comparison of macrophage-specific INH-induced genes to in vitro stimuli-induced genes

In vitro stimulus	Reference list size	Overlap with macrophage-specific INH-induced list	Overlap by random chance	Overlap significance
Acid stress^{^a}	291	35	8	P < 0.001
Nutrient starvation^{^b}	440	37	12	P < 0.001
Oxidative stress (H₂O₂)^{^c}	319	24	9	P < 0.001
NO/CO/hypoxia^{^d}	50	16	1	P < 0.001
SDS-mediated membrane damage^{^e}	211	30	6	P < 0.001
Triton X-100–mediated membrane damage^{^f}	73	20	2	P < 0.001

In vitro stimulus	Reference list size	Overlap with macrophage-specific INH-induced list	Overlap by random chance	Overlap significance
Acid stress^{^a}	291	35	8	P < 0.001
Nutrient starvation^{^b}	440	37	12	P < 0.001
Oxidative stress (H₂O₂)^{^c}	319	24	9	P < 0.001
NO/CO/hypoxia^{^d}	50	16	1	P < 0.001
SDS-mediated membrane damage^{^e}	211	30	6	P < 0.001
Triton X-100–mediated membrane damage^{^f}	73	20	2	P < 0.001

Data from Rohde et al. (2007).

Data from Betts et al. (2002) and Hampshire et al. (2004).

Data from Schnappinger et al. (2003) and Voskuil et al. (2011)

Data from Sherman et al. (2001), Ohno et al. (2003), Park et al. (2003), Voskuil et al. (2003), Kumar et al. (2008), and Shiloh et al. (2008).

Data from Manganelli et al. (2001) and He et al. (2006).

Data from He et al. (2006).