Table 1.

Blood counts of K3+/+ and K3−/− (moribund and healthy) chimeras

Tests K3+/+ chimera K3−/− chimera (healthy) K3−/− chimera (moribund) P-value K3+/+ versus K3−/− (healthy) Normal range 
WBC (103/µl) 9.9 ± 2.6 35.9 ± 16.8 13.9 ± 9.7 <0.0001 1.8–10.7 
NE (103/µl) 2.0 ± 0.9 17.6 ± 6.9 7.3 ± 6.5 <0.0001 0.1–2.4 
LY (103/µl) 7.6 ± 2.3 15.2 ± 8.9 5.1 ± 4.3 0.0016 0.9–9.3 
RBC (103/µl) 8.6 ± 0.5 6.4 ± 1.0 1.6 ± 0.8 <0.0001 6.36–9.42 
Hb (g/dl) 13.0 ± 1.0 11.4 ± 1.5 3.8 ± 2.1 0.0024 11.0–15.1 
HCT (%) 41.4 ± 2.3 35.0 ± 4.4 12.1 ± 6.6 <0.0001 35.1–45.4 
MCV (fl) 48.4 ± 0.9 54.6 ± 3.4 106.3 ± 120.9 <0.0001 45.4–60.3 
MCH (pg) 15.2 ± 0.6 17.8 ± 1.3 23.8 ± 5.2 <0.0001 14.1–19.3 
PLT (103/µl) 589.1 ± 141.9 739.0 ± 77.0 546.1 ± 238.6 0.0058 592–2,972 
Tests K3+/+ chimera K3−/− chimera (healthy) K3−/− chimera (moribund) P-value K3+/+ versus K3−/− (healthy) Normal range 
WBC (103/µl) 9.9 ± 2.6 35.9 ± 16.8 13.9 ± 9.7 <0.0001 1.8–10.7 
NE (103/µl) 2.0 ± 0.9 17.6 ± 6.9 7.3 ± 6.5 <0.0001 0.1–2.4 
LY (103/µl) 7.6 ± 2.3 15.2 ± 8.9 5.1 ± 4.3 0.0016 0.9–9.3 
RBC (103/µl) 8.6 ± 0.5 6.4 ± 1.0 1.6 ± 0.8 <0.0001 6.36–9.42 
Hb (g/dl) 13.0 ± 1.0 11.4 ± 1.5 3.8 ± 2.1 0.0024 11.0–15.1 
HCT (%) 41.4 ± 2.3 35.0 ± 4.4 12.1 ± 6.6 <0.0001 35.1–45.4 
MCV (fl) 48.4 ± 0.9 54.6 ± 3.4 106.3 ± 120.9 <0.0001 45.4–60.3 
MCH (pg) 15.2 ± 0.6 17.8 ± 1.3 23.8 ± 5.2 <0.0001 14.1–19.3 
PLT (103/µl) 589.1 ± 141.9 739.0 ± 77.0 546.1 ± 238.6 0.0058 592–2,972 

Values shown are the mean ± SD for 10–15 mice per genotype. WBC, white blood cell; NE, neutrophil; LY, lymphocyte; Hb, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; PLT, platelet.

or Create an Account

Close Modal
Close Modal