Table 3. Mutation analysis in UNG / and... | Rockefeller University Press

Table 3.

Mutation analysis in UNG^+/+ and UNG^−/− B cells

Mouse ID	Total^a	WRC+GYW^b	WRCY+RGYW^c
UNG^+/+ 1	6.5	35.1	40.0
UNG^+/+ 2	6.3	31.0	34.8
UNG^+/+ 3	6.2	26.9	30.6
UNG^+/+ 4	5.9	27.8	32.0
UNG^−/− 1	14.6	87.5	100.6
UNG^−/− 2	15.5	92.7	105.8
UNG^−/− 3	13.1	74.4	84.1
UNG^−/− 4	10.3	57.6	65.7
AID^−/− 1	2.5	4.8	4.3
AID^−/− 2	2.6	5.5	5.1

Mouse ID	Total^a	WRC+GYW^b	WRCY+RGYW^c
UNG^+/+ 1	6.5	35.1	40.0
UNG^+/+ 2	6.3	31.0	34.8
UNG^+/+ 3	6.2	26.9	30.6
UNG^+/+ 4	5.9	27.8	32.0
UNG^−/− 1	14.6	87.5	100.6
UNG^−/− 2	15.5	92.7	105.8
UNG^−/− 3	13.1	74.4	84.1
UNG^−/− 4	10.3	57.6	65.7
AID^−/− 1	2.5	4.8	4.3
AID^−/− 2	2.6	5.5	5.1

Total frequency of mutations (×10⁻⁴).

Frequency of mutations (×10⁻⁴) in C or G of WRC or GYW hotspots.

Frequency of mutations (×10⁻⁴) in C or G of WRCY or RGYW hotspots.