Patient and disease characteristics of SMZL patients according to NOTCH2 mutational status
| Total | Positive | Negative | Student’s t test | |||||||
| Average | St Dev | n | Average | St Dev | n | Average | St Dev | n | P-value | |
| Percent male | 35% | 71 | 22% | 18 | 40% | 53 | 0.19 | |||
| Age at diagnosis | 62 | 12 | 71 | 63 | 9 | 18 | 61 | 13 | 53 | 0.63 |
| Age at splenectomy | 63 | 12 | 71 | 65 | 10 | 18 | 63 | 12 | 50 | 0.62 |
| Stage at diagnosis | 3.7 | 0.8 | 56 | 3.5 | 1.1 | 13 | 3.8 | 0.7 | 43 | 0.39 |
| International Prognostic | 2.4 | 0.9 | 43 | 2.3 | 1.0 | 9 | 2.5 | 0.9 | 34 | 0.68 |
| Index/Follicular Lymphoma | ||||||||||
| International Prognostic | ||||||||||
| Index | ||||||||||
| Hemoglobin, g/deciliter | 11.8 | 2.0 | 51 | 11.7 | 1.7 | 11 | 11.9 | 2.1 | 40 | 0.77 |
| Lactate dehydrogenase (U/liter) | 328 | 154 | 42 | 321 | 122 | 8 | 330 | 162 | 34 | 0.89 |
| Albumin (g/deciliter) | 4.2 | 0.5 | 19 | 4.4 | 0.4 | 4 | 4.2 | 0.5 | 15 | 0.63 |
| White blood cell (K/mm3) | 18.7 | 23.9 | 21 | 11.2 | 6.8 | 5 | 21.0 | 26.9 | 16 | 0.44 |
| Platelet (K/mm3) | 201 | 109 | 19 | 160 | 50 | 4 | 213 | 119 | 15 | 0.41 |
| β2-microglobulin (mg/liter) | 3.8 | 1.5 | 19 | 3.5 | 1.9 | 4 | 3.9 | 1.4 | 15 | 0.68 |
| Total | Positive | Negative | Student’s t test | |||||||
| Average | St Dev | n | Average | St Dev | n | Average | St Dev | n | P-value | |
| Percent male | 35% | 71 | 22% | 18 | 40% | 53 | 0.19 | |||
| Age at diagnosis | 62 | 12 | 71 | 63 | 9 | 18 | 61 | 13 | 53 | 0.63 |
| Age at splenectomy | 63 | 12 | 71 | 65 | 10 | 18 | 63 | 12 | 50 | 0.62 |
| Stage at diagnosis | 3.7 | 0.8 | 56 | 3.5 | 1.1 | 13 | 3.8 | 0.7 | 43 | 0.39 |
| International Prognostic | 2.4 | 0.9 | 43 | 2.3 | 1.0 | 9 | 2.5 | 0.9 | 34 | 0.68 |
| Index/Follicular Lymphoma | ||||||||||
| International Prognostic | ||||||||||
| Index | ||||||||||
| Hemoglobin, g/deciliter | 11.8 | 2.0 | 51 | 11.7 | 1.7 | 11 | 11.9 | 2.1 | 40 | 0.77 |
| Lactate dehydrogenase (U/liter) | 328 | 154 | 42 | 321 | 122 | 8 | 330 | 162 | 34 | 0.89 |
| Albumin (g/deciliter) | 4.2 | 0.5 | 19 | 4.4 | 0.4 | 4 | 4.2 | 0.5 | 15 | 0.63 |
| White blood cell (K/mm3) | 18.7 | 23.9 | 21 | 11.2 | 6.8 | 5 | 21.0 | 26.9 | 16 | 0.44 |
| Platelet (K/mm3) | 201 | 109 | 19 | 160 | 50 | 4 | 213 | 119 | 15 | 0.41 |
| β2-microglobulin (mg/liter) | 3.8 | 1.5 | 19 | 3.5 | 1.9 | 4 | 3.9 | 1.4 | 15 | 0.68 |
Summary of available clinical, histopathological, and laboratory parameters for SMZL patients is shown according to NOTCH2 mutational status. No statisticlly significant differences were noted. St Dev, standard deviation.