Table 2.

Patient and disease characteristics of SMZL patients according to NOTCH2 mutational status

 Total Positive Negative Student’s t test 
 Average St Dev n Average St Dev n Average St Dev n P-value 
Percent male 35%  71 22%  18 40%  53 0.19 
Age at diagnosis 62 12 71 63 9 18 61 13 53 0.63 
Age at splenectomy 63 12 71 65 10 18 63 12 50 0.62 
Stage at diagnosis 3.7 0.8 56 3.5 1.1 13 3.8 0.7 43 0.39 
International Prognostic 2.4 0.9 43 2.3 1.0 9 2.5 0.9 34 0.68 
 Index/Follicular Lymphoma           
 International Prognostic           
 Index           
Hemoglobin, g/deciliter 11.8 2.0 51 11.7 1.7 11 11.9 2.1 40 0.77 
Lactate dehydrogenase (U/liter) 328 154 42 321 122 8 330 162 34 0.89 
Albumin (g/deciliter) 4.2 0.5 19 4.4 0.4 4 4.2 0.5 15 0.63 
White blood cell (K/mm3) 18.7 23.9 21 11.2 6.8 5 21.0 26.9 16 0.44 
Platelet (K/mm3) 201 109 19 160 50 4 213 119 15 0.41 
β2-microglobulin (mg/liter) 3.8 1.5 19 3.5 1.9 4 3.9 1.4 15 0.68 

Summary of available clinical, histopathological, and laboratory parameters for SMZL patients is shown according to NOTCH2 mutational status. No statisticlly significant differences were noted. St Dev, standard deviation.

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