Table 2.

Mutation analysis in AID and AIDE58Q expressing NIH-3T3 cells

Experiment Totala WRC+GYWb WRCY+RGYWc 
 AID AIDE58Q AID AIDE58Q AID AIDE58Q 
8.9 4.4 39.8 6.0 57.8 5.9 
5.8 3.3 21.5 4.5 30.1 4.4 
14.9 6.6 73.0 7.3 106.7 7.4 
Experiment Totala WRC+GYWb WRCY+RGYWc 
 AID AIDE58Q AID AIDE58Q AID AIDE58Q 
8.9 4.4 39.8 6.0 57.8 5.9 
5.8 3.3 21.5 4.5 30.1 4.4 
14.9 6.6 73.0 7.3 106.7 7.4 
a

Total frequency of mutations (×10−4).

b

Frequency of mutations (×10−4) in C or G of WRC or GYW hotspots.

c

Frequency of mutations (×10−4) in C or G of WRCY or RGYW hotspots.

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