Table 1.

Quantification of thymocyte subsets in WT (Satb1fl/fl) and Satb1−/− (Satb1f/fVav-Cre) micea

Cell population WT (×10−5Satb1−/− (×10−5
Total thymocytes (n = 6-7) 1,730 ± 610 670 ± 300b 
DN1 (n = 3-4) 0.45 ± 0.30 0.20 ± 0.17 
DN2 (n = 3-4) 0.89 ± 0.10 0.11 ± 0.10c 
DN3 (n = 3-4) 17.9 ± 10.3 5.1 ± 3.4 
CD8 ISP (n = 5-6) 22.0 ± 11.3 12.4 ± 9.1 
DP (n = 6-7) 1,460 ± 500 570 ± 250b 
CD4 SP (n = 6-7) 109 ± 49 17 ± 7c 
CD8 SP (n = 6-7) 28.2 ± 11.6 2.7 ± 2.1c 
Cell population WT (×10−5Satb1−/− (×10−5
Total thymocytes (n = 6-7) 1,730 ± 610 670 ± 300b 
DN1 (n = 3-4) 0.45 ± 0.30 0.20 ± 0.17 
DN2 (n = 3-4) 0.89 ± 0.10 0.11 ± 0.10c 
DN3 (n = 3-4) 17.9 ± 10.3 5.1 ± 3.4 
CD8 ISP (n = 5-6) 22.0 ± 11.3 12.4 ± 9.1 
DP (n = 6-7) 1,460 ± 500 570 ± 250b 
CD4 SP (n = 6-7) 109 ± 49 17 ± 7c 
CD8 SP (n = 6-7) 28.2 ± 11.6 2.7 ± 2.1c 
a

Vav-Cre transgenic mice have no intrinsic thymic phenotype (de Boer et al., 2003).

b

P < 0.01 when compared with WT counterparts (Student’s t test).

c

P < 0.001 when compared with WT counterparts (Student’s t test).

or Create an Account

Close Modal
Close Modal