Table 1.
Hematopoietic parameters
ParameterInsr+/+ (n = 12)Insr–/– (n = 12)P-value
Blood    
 WBC (×103/µl) 12.6 ± 1.5 27.8 ± 3.4 0.00014 
 RBC (×106/µl)  9.3 ± 1.2 10.9 ± 1.5 0.17293 
 Hemoglobin (g/dl)  16.0 ± 2.3 19.1 ± 1.6 0.09752 
 Hematocrit (%)  53.0 ± 3.7 56.7 ± 2.8 0.13923 
Differential WBC (%)    
 Lymphocytes 69.0 ± 4.3 17.8 ± 3.2 8.65 × 10−8 
 Neutrophils 24.1 ± 1.6 58.9 ± 5.5 9.12 × 10−7 
 Monocytes 3.9 ± 0.7 16.0 ± 0.9 2.68 × 10−10 
 Eosinophil  1.5 ± 0.1 8.0 ± 0.6 1.91 × 10−8 
Tissues    
 WBC/femur (×103/µl)  20.9 ± 1.6 51.8 ± 3.3 3.17 × 10−8 
 Spleen (mg) 93.7 ± 5.4 384.4 ± 18.5 1.84 × 10−12 
ParameterInsr+/+ (n = 12)Insr–/– (n = 12)P-value
Blood    
 WBC (×103/µl) 12.6 ± 1.5 27.8 ± 3.4 0.00014 
 RBC (×106/µl)  9.3 ± 1.2 10.9 ± 1.5 0.17293 
 Hemoglobin (g/dl)  16.0 ± 2.3 19.1 ± 1.6 0.09752 
 Hematocrit (%)  53.0 ± 3.7 56.7 ± 2.8 0.13923 
Differential WBC (%)    
 Lymphocytes 69.0 ± 4.3 17.8 ± 3.2 8.65 × 10−8 
 Neutrophils 24.1 ± 1.6 58.9 ± 5.5 9.12 × 10−7 
 Monocytes 3.9 ± 0.7 16.0 ± 0.9 2.68 × 10−10 
 Eosinophil  1.5 ± 0.1 8.0 ± 0.6 1.91 × 10−8 
Tissues    
 WBC/femur (×103/µl)  20.9 ± 1.6 51.8 ± 3.3 3.17 × 10−8 
 Spleen (mg) 93.7 ± 5.4 384.4 ± 18.5 1.84 × 10−12 

Differential WBCs were determined by monitoring the morphology of cells stained with May-Grunewald Giemsa. Data are shown as means ± SD.

or Create an Account

Close Modal
Close Modal