Profile of lipid mediators in human plasma of healthy volunteers taking dietary EPA at 2.7 g/day
| EPA-derived lipid mediator | EPA 0w (pg/ml) | EPA 2w (pg/ml) | P value |
| PGE3 | 26.4 ± 5.9 | 32.0 ± 13.2 | 0.699428347 |
| PGD3 | 7.2 ± 2.7 | 9.9 ± 3.4 | 0.506270699 |
| PGF3α | 90.3 ± 33.8 | 80.5 ± 44.2 | 0.825358514 |
| 6-keto-PGF1a-17delta | 72.4 ± 48.4 | 80.6 ± 71.4 | 0.772022261 |
| TXB3 | 10.8 ± 3.6 | 16.6 ± 6.8 | 0.243550461 |
| LTB5 | 7.6 ± 1.6 | 10.9 ± 1.5 | 0.301981898 |
| LXA5 | 3.2 ± 1.5 | 15.2 ± 5.7 | 0.526795284 |
| RvE2 | 10.1 ± 4.1 | 24.9 ± 13.5 | 0.397489159 |
| RvE3 | 55.3 ± 8.5 | 42.3 ± 13.8 | 0.349509121 |
| 5-HEPE | 309.7 ± 84.2 | 270.1 ± 51.8 | 0.756489821 |
| 8-HEPE | 48.7 ± 13.3 | 88.9 ± 25.7 | 0.060813559 |
| 9-HEPE | 55.0 ± 18.1 | 95.3 ± 17.9 | 0.151960325 |
| 8,9-EpETE | 29.6 ± 10.0 | 68.7 ± 37.7 | 0.341822254 |
| 11-HEPE | 36.3 ± 9.1 | 44.0 ± 8.9 | 0.471267817 |
| 12-HEPE | 58.8 ± 17.5 | 72.2 ± 12.8 | 0.351678213 |
| 11,12-EpETE | 109.9 ± 27.2 | 257.5 ± 138.6 | 0.335749115 |
| 15-HEPE | 149.3 ± 24.4 | 188.2 ± 36.0 | 0.346843422 |
| 14,15-EpETE | 46.8 ± 14.6 | 131.5 ± 86.8 | 0.416135401 |
| 18-HEPE | 95.6 ± 23.7 | 149.0 ± 12.7 | 0.000720547 |
| 17,18-EpETE | 144.8 ± 46.3 | 220.3 ± 98.1 | 0.463858736 |
| 17,18-diHETE | 3855.4 ± 371.3 | 7364.9 ± 928.5 | 0.002201551 |
| 19-HEPE | 584.5 ± 126.9 | 1205.3 ± 195.8 | 0.038534813 |
| 20-HEPE | 189.3 ± 62.5 | 266.4 ± 30.3 | 0.153533361 |
| 5,15-diHEPE | 9.9 ± 3.4 | 20.2 ± 7.3 | 0.372063162 |
| 8,15-diHEPE | 37.7 ± 5.6 | 32.7 ± 9.5 | 0.618181239 |
| 8,18-diHEPE | 6.8 ± 3.3 | 15.3 ± 4.9 | 0.068913138 |
| 12,18-diHEPE | 11.1 ± 4.9 | 24.7 ± 5.6 | 0.068628042 |
| EPA-derived lipid mediator | EPA 0w (pg/ml) | EPA 2w (pg/ml) | P value |
| PGE3 | 26.4 ± 5.9 | 32.0 ± 13.2 | 0.699428347 |
| PGD3 | 7.2 ± 2.7 | 9.9 ± 3.4 | 0.506270699 |
| PGF3α | 90.3 ± 33.8 | 80.5 ± 44.2 | 0.825358514 |
| 6-keto-PGF1a-17delta | 72.4 ± 48.4 | 80.6 ± 71.4 | 0.772022261 |
| TXB3 | 10.8 ± 3.6 | 16.6 ± 6.8 | 0.243550461 |
| LTB5 | 7.6 ± 1.6 | 10.9 ± 1.5 | 0.301981898 |
| LXA5 | 3.2 ± 1.5 | 15.2 ± 5.7 | 0.526795284 |
| RvE2 | 10.1 ± 4.1 | 24.9 ± 13.5 | 0.397489159 |
| RvE3 | 55.3 ± 8.5 | 42.3 ± 13.8 | 0.349509121 |
| 5-HEPE | 309.7 ± 84.2 | 270.1 ± 51.8 | 0.756489821 |
| 8-HEPE | 48.7 ± 13.3 | 88.9 ± 25.7 | 0.060813559 |
| 9-HEPE | 55.0 ± 18.1 | 95.3 ± 17.9 | 0.151960325 |
| 8,9-EpETE | 29.6 ± 10.0 | 68.7 ± 37.7 | 0.341822254 |
| 11-HEPE | 36.3 ± 9.1 | 44.0 ± 8.9 | 0.471267817 |
| 12-HEPE | 58.8 ± 17.5 | 72.2 ± 12.8 | 0.351678213 |
| 11,12-EpETE | 109.9 ± 27.2 | 257.5 ± 138.6 | 0.335749115 |
| 15-HEPE | 149.3 ± 24.4 | 188.2 ± 36.0 | 0.346843422 |
| 14,15-EpETE | 46.8 ± 14.6 | 131.5 ± 86.8 | 0.416135401 |
| 18-HEPE | 95.6 ± 23.7 | 149.0 ± 12.7 | 0.000720547 |
| 17,18-EpETE | 144.8 ± 46.3 | 220.3 ± 98.1 | 0.463858736 |
| 17,18-diHETE | 3855.4 ± 371.3 | 7364.9 ± 928.5 | 0.002201551 |
| 19-HEPE | 584.5 ± 126.9 | 1205.3 ± 195.8 | 0.038534813 |
| 20-HEPE | 189.3 ± 62.5 | 266.4 ± 30.3 | 0.153533361 |
| 5,15-diHEPE | 9.9 ± 3.4 | 20.2 ± 7.3 | 0.372063162 |
| 8,15-diHEPE | 37.7 ± 5.6 | 32.7 ± 9.5 | 0.618181239 |
| 8,18-diHEPE | 6.8 ± 3.3 | 15.3 ± 4.9 | 0.068913138 |
| 12,18-diHEPE | 11.1 ± 4.9 | 24.7 ± 5.6 | 0.068628042 |