Reads depth of the identified variants that passed the whole-exome filtering strategy consisting of selecting candidate variants that were nonsynonymous variants, frameshifts/insertions/deletions affecting coding regions, that were absent or reported at a low frequency (<1‰) in public databases (including the 1000 Genomes project and the Exome Variant Server), and that were found in the homozygous state in the two affected siblings (with a minimum depth of 10X) but which were heterozygous in the two unaffected parents. NA indicates that the individual is not carrying the identified variant.