The frequency of human H chains with Arg in CDR3 in antibodies expressing Vκ editor, Vκ non-editor, and Vλ 5-6 human L chains from sorted peripheral blood
| B cell population that expresses: | Number of H chain sequences analyzed | Number of H chains with Arg in CDR3 |
| Vκ editors | 72 | 43 (60%)* |
| Vκ non-editors | 194 | 77 (40%) |
| Vλ 5-6 | 142 | 47 (33%) |
| B cell population that expresses: | Number of H chain sequences analyzed | Number of H chains with Arg in CDR3 |
| Vκ editors | 72 | 43 (60%)* |
| Vκ non-editors | 194 | 77 (40%) |
| Vλ 5-6 | 142 | 47 (33%) |
The number and percentage of H chains with Arg in CDR3 region in antibodies expressing Vκ editor, Vκ non-editor, and Vλ 5-6 L chains are shown. The CDR regions were identified according to the Kabat numbering scheme. *, P < 0.005, χ2 test.
Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.