Table 3. Role of CDK-mediated... | Rockefeller University Press

Table 3.

Role of CDK-mediated phosphorylation of CtIP at T847 on embryonic viability

	CtIP^T847ACtIP^+/− x CtIP^+/−
Genotype	CtIP^−/−	CtIP^−/−	CtIP^+/+	CtIP^T847A CtIP^−/−	CtIP^T847A CtIP^+/−	CtIP^T847A CtIP^+/+
E9.5 embryos
Observed	0	2	1	0	14	6
Expected	2.875	5.75	2.875	2.875	5.75	2.875
Total embryos screened	23

	CtIP^T847ACtIP^+/− x CtIP^+/−
Genotype	CtIP^−/−	CtIP^−/−	CtIP^+/+	CtIP^T847A CtIP^−/−	CtIP^T847A CtIP^+/−	CtIP^T847A CtIP^+/+
E9.5 embryos
Observed	0	2	1	0	14	6
Expected	2.875	5.75	2.875	2.875	5.75	2.875
Total embryos screened	23

CtIP heterozygous mice were intercrossed with one parent carrying a copy of the transgenic CtIP-T847A mutation, and embryos were genotyped at E9.5.