Table 4.

Characteristics of three lines of mutant Nlrc4 transgenic mice

Mouse line Expression of Nlrc4 (fold increases compared with wild type) Spleen cells (×107T cells (×107CD11b+Gr1+ cells (×107
Wild type 5.2 ± 0.3 0.8 ± 0.1 0.05 ± 0.01 
Line #1 3.1 ± 0.2 21.1 ± 1.4 3.4 ± 0.4 0.59 ± 0.2 
Line #2 5.2 ± 0.3 32.1 ± 3.3 5.4 ± 2.2 1.2 ± 0.2 
Line #3 4.2 ± 0.3 27.8 ± 4.5 4.5 ± 0.4 0.89 ± 0.1 
Mouse line Expression of Nlrc4 (fold increases compared with wild type) Spleen cells (×107T cells (×107CD11b+Gr1+ cells (×107
Wild type 5.2 ± 0.3 0.8 ± 0.1 0.05 ± 0.01 
Line #1 3.1 ± 0.2 21.1 ± 1.4 3.4 ± 0.4 0.59 ± 0.2 
Line #2 5.2 ± 0.3 32.1 ± 3.3 5.4 ± 2.2 1.2 ± 0.2 
Line #3 4.2 ± 0.3 27.8 ± 4.5 4.5 ± 0.4 0.89 ± 0.1 

The data were obtained at the age of 16 wk. The data in line #1 are used in all figures.

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