Table 1. Analyses of plasma and feces... | Rockefeller University Press

Table 1.

Analyses of plasma and feces from transgenic and littermate mice 12 d after DTX administration

Parameter	Littermates	Transgenics	P-value	Normal range
Gamma glutamyl peptidase (U/liter)	0.2 ± 0.2	0.0 ± 0.0	0.35	0.0–0.2
Aspartate aminotransferase (U/liter)	150.0 ± 45.1	167.2 ± 28.2	0.75	59–247
Alanine aminotransferase (U/liter)	24.4 ± 3.1	114.6 ± 51.3	0.12	28–132
Urea nitrogen (mmol/liter)	7.2 ± 0.5	6.1 ± 0.6	0.79	6.4–10.4
Glucose (mmol/liter)	15.0 ± 0.2	14.1 ± 0.8	0.38	9.0–19.3
Insulin (µg/liter)	0.3 ± 0.1	0.3 ± 0.1	0.61	0.1–2.9
Albumin (g/liter)	27.6 ± 2.0	26.6 ± 1.2	0.68	25–48
Bilirubin (µmol/liter)	6.4 ± 0.9	6.0 ± 1.0	0.78	2–15
Total protein (g/liter)	51.0 ± 2.3	52.2 ± 0.6	0.62	36–66
Phosphate (mmol/liter)	2.1 ± 0.1	2.6 ± 0.2	0.10	1.97–3.26
Calcium (mmol/liter)	2.0 ± 0.1	1.9 ± 0.1	0.26	1.47–2.35
Fecal energy (kJ/g)	13.7 ± 0.7	13.7 ± 0.5	0.98

Parameter	Littermates	Transgenics	P-value	Normal range
Gamma glutamyl peptidase (U/liter)	0.2 ± 0.2	0.0 ± 0.0	0.35	0.0–0.2
Aspartate aminotransferase (U/liter)	150.0 ± 45.1	167.2 ± 28.2	0.75	59–247
Alanine aminotransferase (U/liter)	24.4 ± 3.1	114.6 ± 51.3	0.12	28–132
Urea nitrogen (mmol/liter)	7.2 ± 0.5	6.1 ± 0.6	0.79	6.4–10.4
Glucose (mmol/liter)	15.0 ± 0.2	14.1 ± 0.8	0.38	9.0–19.3
Insulin (µg/liter)	0.3 ± 0.1	0.3 ± 0.1	0.61	0.1–2.9
Albumin (g/liter)	27.6 ± 2.0	26.6 ± 1.2	0.68	25–48
Bilirubin (µmol/liter)	6.4 ± 0.9	6.0 ± 1.0	0.78	2–15
Total protein (g/liter)	51.0 ± 2.3	52.2 ± 0.6	0.62	36–66
Phosphate (mmol/liter)	2.1 ± 0.1	2.6 ± 0.2	0.10	1.97–3.26
Calcium (mmol/liter)	2.0 ± 0.1	1.9 ± 0.1	0.26	1.47–2.35
Fecal energy (kJ/g)	13.7 ± 0.7	13.7 ± 0.5	0.98

Data are representative of two independent analyses and are expressed as mean ± SEM (n ≥ 5). Fecal energy does not have a well-established normal range as it differs depending on chow so much. As a result, we have simply compared with littermate controls as these were fed at the same time with the same chow.

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