Analyses of plasma and feces from transgenic and littermate mice 12 d after DTX administration
| Parameter | Littermates | Transgenics | P-value | Normal range |
| Gamma glutamyl peptidase (U/liter) | 0.2 ± 0.2 | 0.0 ± 0.0 | 0.35 | 0.0–0.2 |
| Aspartate aminotransferase (U/liter) | 150.0 ± 45.1 | 167.2 ± 28.2 | 0.75 | 59–247 |
| Alanine aminotransferase (U/liter) | 24.4 ± 3.1 | 114.6 ± 51.3 | 0.12 | 28–132 |
| Urea nitrogen (mmol/liter) | 7.2 ± 0.5 | 6.1 ± 0.6 | 0.79 | 6.4–10.4 |
| Glucose (mmol/liter) | 15.0 ± 0.2 | 14.1 ± 0.8 | 0.38 | 9.0–19.3 |
| Insulin (µg/liter) | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.61 | 0.1–2.9 |
| Albumin (g/liter) | 27.6 ± 2.0 | 26.6 ± 1.2 | 0.68 | 25–48 |
| Bilirubin (µmol/liter) | 6.4 ± 0.9 | 6.0 ± 1.0 | 0.78 | 2–15 |
| Total protein (g/liter) | 51.0 ± 2.3 | 52.2 ± 0.6 | 0.62 | 36–66 |
| Phosphate (mmol/liter) | 2.1 ± 0.1 | 2.6 ± 0.2 | 0.10 | 1.97–3.26 |
| Calcium (mmol/liter) | 2.0 ± 0.1 | 1.9 ± 0.1 | 0.26 | 1.47–2.35 |
| Fecal energy (kJ/g) | 13.7 ± 0.7 | 13.7 ± 0.5 | 0.98 |
| Parameter | Littermates | Transgenics | P-value | Normal range |
| Gamma glutamyl peptidase (U/liter) | 0.2 ± 0.2 | 0.0 ± 0.0 | 0.35 | 0.0–0.2 |
| Aspartate aminotransferase (U/liter) | 150.0 ± 45.1 | 167.2 ± 28.2 | 0.75 | 59–247 |
| Alanine aminotransferase (U/liter) | 24.4 ± 3.1 | 114.6 ± 51.3 | 0.12 | 28–132 |
| Urea nitrogen (mmol/liter) | 7.2 ± 0.5 | 6.1 ± 0.6 | 0.79 | 6.4–10.4 |
| Glucose (mmol/liter) | 15.0 ± 0.2 | 14.1 ± 0.8 | 0.38 | 9.0–19.3 |
| Insulin (µg/liter) | 0.3 ± 0.1 | 0.3 ± 0.1 | 0.61 | 0.1–2.9 |
| Albumin (g/liter) | 27.6 ± 2.0 | 26.6 ± 1.2 | 0.68 | 25–48 |
| Bilirubin (µmol/liter) | 6.4 ± 0.9 | 6.0 ± 1.0 | 0.78 | 2–15 |
| Total protein (g/liter) | 51.0 ± 2.3 | 52.2 ± 0.6 | 0.62 | 36–66 |
| Phosphate (mmol/liter) | 2.1 ± 0.1 | 2.6 ± 0.2 | 0.10 | 1.97–3.26 |
| Calcium (mmol/liter) | 2.0 ± 0.1 | 1.9 ± 0.1 | 0.26 | 1.47–2.35 |
| Fecal energy (kJ/g) | 13.7 ± 0.7 | 13.7 ± 0.5 | 0.98 |
Data are representative of two independent analyses and are expressed as mean ± SEM (n ≥ 5). Fecal energy does not have a well-established normal range as it differs depending on chow so much. As a result, we have simply compared with littermate controls as these were fed at the same time with the same chow.