Table 1. MHC II tetramer reagents Virus... | Rockefeller University Press

Table 1.

MHC II tetramer reagents

Virus phase	Protein	Coordinates	Epitope^a	MHC II restriction^b
Latent	EBNA1 (E1)	474–493	SNPKFENIAEGLRVLLARSH	DRB5*01:01 (DR51)
Latent	EBNA1 (E1)	509–528	VYGGSKTSLYNLRRGTALAI	DRB1*07:01 (DR7)
Latent	EBNA2 (E2)	276–295	PRSPTVFYNIPPMPLPPSQL	DRB1*07:01 (DR7)
Latent	EBNA2 (E2)	276–295	PRSPTVFYNIPPMPLPPSQL	DRB3*02:02 (DR52b)
Latent	EBNA2 (E2)	301–320	PAQPPPGVINDQQLHHLPSG	DRB1*03:01 (DR17)
Lytic	BZLF1 (BZ)	61–75	LTAYHVSTAPTGSWF	DRB3*02:02 (DR52b)
Lytic	BMRF1 (BM)	136–150	VKLTMEYDDKVSKSH	DRB1*03:01 (DR17)
Lytic	BaRF1 (Ba)	185–199	SRDELLHTRAASLLY	DRB1*07:01 (DR7)
Lytic	BFRF1 (BF)	125–139	MLGQDDFIKFKSPLV	DRB1*07:01 (DR7)

Virus phase	Protein	Coordinates	Epitope^a	MHC II restriction^b
Latent	EBNA1 (E1)	474–493	SNPKFENIAEGLRVLLARSH	DRB5*01:01 (DR51)
Latent	EBNA1 (E1)	509–528	VYGGSKTSLYNLRRGTALAI	DRB1*07:01 (DR7)
Latent	EBNA2 (E2)	276–295	PRSPTVFYNIPPMPLPPSQL	DRB1*07:01 (DR7)
Latent	EBNA2 (E2)	276–295	PRSPTVFYNIPPMPLPPSQL	DRB3*02:02 (DR52b)
Latent	EBNA2 (E2)	301–320	PAQPPPGVINDQQLHHLPSG	DRB1*03:01 (DR17)
Lytic	BZLF1 (BZ)	61–75	LTAYHVSTAPTGSWF	DRB3*02:02 (DR52b)
Lytic	BMRF1 (BM)	136–150	VKLTMEYDDKVSKSH	DRB1*03:01 (DR17)
Lytic	BaRF1 (Ba)	185–199	SRDELLHTRAASLLY	DRB1*07:01 (DR7)
Lytic	BFRF1 (BF)	125–139	MLGQDDFIKFKSPLV	DRB1*07:01 (DR7)

All epitopes are hereby referred to by the first three amino acids of their sequence, as underlined.

PCR and serological MHC II types (brackets) are given for each restriction.