Table 1.

Calculation of the use of DFL16.1 in RF1 relative to the WT mice

Genotype (alleles A/B) Allele A Allele B R value 
 R1 R2 R3 R1 R2 R3  
ΔD-DFL/ΔD-DFLa 
ΔD-DFL/WT 
WT/WT 
ΔD-DµFS/WT 0.59 0.33 0.99 
ΔD-DµFSD-DµFSb 0.59 0.33 0.59 0.33 0.97 
ΔD-iD/WT 0.48 0.5 
ΔD-iDD-iDc 0.48 0.48 
Genotype (alleles A/B) Allele A Allele B R value 
 R1 R2 R3 R1 R2 R3  
ΔD-DFL/ΔD-DFLa 
ΔD-DFL/WT 
WT/WT 
ΔD-DµFS/WT 0.59 0.33 0.99 
ΔD-DµFSD-DµFSb 0.59 0.33 0.59 0.33 0.97 
ΔD-iD/WT 0.48 0.5 
ΔD-iDD-iDc 0.48 0.48 

R1 is the proportion of mature recirculating IgM+ IgD+ B cells in the bone marrow relative to WT. R2 is the expected frequency of DFL16.1 gene usage relative to WT. R3 is the expected frequency of RF1 usage relative to WT. The formula used to calculate the R value is [Rallele A (R1 × R2 × R3) + Rallele B (R1 × R2 × R3)] × 0.5.

a

The data used to calculate the R1, R2, and R3 values were retrieved from Schelonka et al. (2005).

b

The data used to calculate the R1, R2, and R3 values were retrieved from Schelonka et al. (2008) and Zemlin et al. (2008).

c

The data used to calculate the R1, R2, and R3 values were retrieved from Ippolito et al. (2006).

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