Table I.

Proteins copurifying with AID-Flag-HA from Ramos B cells identified by mass spectrometry

HUGO name Mascot score Coverage Description 
  %  
HSP90AB1 2,178 44 Heat shock 90-kD protein 1, β 
 300  
HSP90AA1 1,668 35 Heat shock 90-kD protein 1, α 
 151  
HSPA8 1,338 39 Heat shock 70-kD protein 8 isoform 1 
HSPA6 327 Heat shock 70-kD protein B 
AHSA1 81 AHA-1 activator of heat shock 90-kD protein ATPase homologue 1 
 27  
DNAJA1 212 26 Hsp40 homologue, subfamily A, member 1 
PSMD2 242 14 Proteasome 26S non-ATPase subunit 2 
PSMD1 105 Proteasome 26S non-ATPase subunit 1 
PSMD6 105 Proteasome 26S non-ATPase subunit 6 
 46  
PSMC2 75 Proteasome 26S ATPase subunit 2 
HUGO name Mascot score Coverage Description 
  %  
HSP90AB1 2,178 44 Heat shock 90-kD protein 1, β 
 300  
HSP90AA1 1,668 35 Heat shock 90-kD protein 1, α 
 151  
HSPA8 1,338 39 Heat shock 70-kD protein 8 isoform 1 
HSPA6 327 Heat shock 70-kD protein B 
AHSA1 81 AHA-1 activator of heat shock 90-kD protein ATPase homologue 1 
 27  
DNAJA1 212 26 Hsp40 homologue, subfamily A, member 1 
PSMD2 242 14 Proteasome 26S non-ATPase subunit 2 
PSMD1 105 Proteasome 26S non-ATPase subunit 1 
PSMD6 105 Proteasome 26S non-ATPase subunit 6 
 46  
PSMC2 75 Proteasome 26S ATPase subunit 2 

Proteins with two rows of data were identified in two independent experiments. The gel from one of the experiments is shown in Fig. 1 A. A threshold Mascot score of 50 was used as cut-off, indicating a 95% confidence of being a true identification. For AHSA1, in the second experiment, the mass spectrometry profile was manually examined to confirm the reliability of the observation.

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