Table 1. DLK-interacting proteins... | Rockefeller University Press

Table 1.

DLK-interacting proteins identified by mass spectrometry

Gene	Uniprot Symbol	Present in PSD	Peptides in DLK^lox:Cre^neg	Peptides in DLK^lox:Cre^pos
DLK	MAP3K12	X	23	1
Beta spectrin 2	Spnb2	X	28	0
LZK	MAP3K13		13	0
Neurofilament light	Nefl	X	13	0
Neurofilament medium	Nefm	X	12	0
Beta spectrin 3	Spnb3	X	10	0
Internexin	Ina	X	9	0
Matrin 3	Matr3		7	0
Purine rich binding protein element A	Pura	X	7	0
Microtubule associate protein 1A	Map1a	X	6	0
Contactin 1	Cntn1	X	5	0
Actinin alpha 1	Actn1	X	5	0
DEAH box polypeptide 9	Dhx9		5	0
Synaptic RAS GTPase activating protein	Syngap1	X	4	0
Microtubule associate protein 4	Map4	X	4	0
Heterogeneous nuclear ribonucleoprotein a2b1	HNRPa2b1		4	0
BR serine/threonine kinase 1	Brsk1		4	0
PSD-95	DLG4	X	3	0
Set binding factor 1	sbf1	X	3	0
Kinesin family member 2A	Kif2	X	2	0

Gene	Uniprot Symbol	Present in PSD	Peptides in DLK^lox:Cre^neg	Peptides in DLK^lox:Cre^pos
DLK	MAP3K12	X	23	1
Beta spectrin 2	Spnb2	X	28	0
LZK	MAP3K13		13	0
Neurofilament light	Nefl	X	13	0
Neurofilament medium	Nefm	X	12	0
Beta spectrin 3	Spnb3	X	10	0
Internexin	Ina	X	9	0
Matrin 3	Matr3		7	0
Purine rich binding protein element A	Pura	X	7	0
Microtubule associate protein 1A	Map1a	X	6	0
Contactin 1	Cntn1	X	5	0
Actinin alpha 1	Actn1	X	5	0
DEAH box polypeptide 9	Dhx9		5	0
Synaptic RAS GTPase activating protein	Syngap1	X	4	0
Microtubule associate protein 4	Map4	X	4	0
Heterogeneous nuclear ribonucleoprotein a2b1	HNRPa2b1		4	0
BR serine/threonine kinase 1	Brsk1		4	0
PSD-95	DLG4	X	3	0
Set binding factor 1	sbf1	X	3	0
Kinesin family member 2A	Kif2	X	2	0

“Present in PSD” denotes peptides identified in PSD fraction after biochemical fractionation. All peptides except DLK and Map4 have been identified in multiple independent studies.

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