Table 2. CTGF expression in MM cells was... | Rockefeller University Press

Table 2.

CTGF expression in MM cells was dominantly observed in sarcomatoid type tissues

No.	Pathological subtype	Features	p-Smad2 (nuclear)	YAP (nuclear)	CTGF (cytoplasm)
1	Sarcomatoid	Fibrous	+	+	+
2	Sarcomatoid	Fibrous	+	+	+
3	Sarcomatoid	Fibrous	+	+	+
4	Sarcomatoid	Fibrous	+	±	+
5	Sarcomatoid	Fibrous	+	±	+
6	Sarcomatoid	Fibrous	+	+	+
7	Sarcomatoid	Fibrous	+	±	+
8	Desmoplastic (sarcomatoid)	Fibrous	+	+	+
9	Desmoplastic (sarcomatoid)	Fibrous	+	+	+
10	Biphasic	Fibrous sarcomatoid, tubulopapillary	+	S: +, E: ±	S: +, E:−
11	Biphasic	Fibrous sarcomatoid, microcystic	+	S: ±, E: ±	S: +, E: +
12	Biphasic	Fibrous sarcomatoid, solid (well-differentiated)	+	S: +, E: +	S: ±, E: ±
13	Epithelioid	Fibrous microcystic	+	+	+
14	Epithelioid	Tubulopapillary	+	−	−
15	Epithelioid	Microcystic, tubulopapillary	+	+	±
16	Epithelioid	Tubulopapillary	+	−	−
17	Epithelioid	Tubulopapillary	+	−	−
18	Epithelioid	Tubulopapillary	+	−	−
19	Epithelioid	Tubulopapillary	+	−	−
20	Epithelioid	Microcystic	+	+	−
21	Epithelioid	Tubulopapillary	+	+	−
22	Epithelioid	Tubulopapillary	+	+	±
23	Epithelioid	Solid (well-differentiated)	+	+	−
24	Epithelioid	Tubulopapillary	+	+	−

No.	Pathological subtype	Features	p-Smad2 (nuclear)	YAP (nuclear)	CTGF (cytoplasm)
1	Sarcomatoid	Fibrous	+	+	+
2	Sarcomatoid	Fibrous	+	+	+
3	Sarcomatoid	Fibrous	+	+	+
4	Sarcomatoid	Fibrous	+	±	+
5	Sarcomatoid	Fibrous	+	±	+
6	Sarcomatoid	Fibrous	+	+	+
7	Sarcomatoid	Fibrous	+	±	+
8	Desmoplastic (sarcomatoid)	Fibrous	+	+	+
9	Desmoplastic (sarcomatoid)	Fibrous	+	+	+
10	Biphasic	Fibrous sarcomatoid, tubulopapillary	+	S: +, E: ±	S: +, E:−
11	Biphasic	Fibrous sarcomatoid, microcystic	+	S: ±, E: ±	S: +, E: +
12	Biphasic	Fibrous sarcomatoid, solid (well-differentiated)	+	S: +, E: +	S: ±, E: ±
13	Epithelioid	Fibrous microcystic	+	+	+
14	Epithelioid	Tubulopapillary	+	−	−
15	Epithelioid	Microcystic, tubulopapillary	+	+	±
16	Epithelioid	Tubulopapillary	+	−	−
17	Epithelioid	Tubulopapillary	+	−	−
18	Epithelioid	Tubulopapillary	+	−	−
19	Epithelioid	Tubulopapillary	+	−	−
20	Epithelioid	Microcystic	+	+	−
21	Epithelioid	Tubulopapillary	+	+	−
22	Epithelioid	Tubulopapillary	+	+	±
23	Epithelioid	Solid (well-differentiated)	+	+	−
24	Epithelioid	Tubulopapillary	+	+	−

Immunohistochemical staining of 24 patients was performed using p-Smad2, YAP, and CTGF antibodies. Tissues were classified based on pathological subtypes. +, positive; ±, partially positive; −, negative; S, sarcomatoid part; E, epithelioid part.

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