Table 1. Blood flow, gases, and pH... | Rockefeller University Press

Table 1.

Blood flow, gases, and pH

Strain	WT (n = 8)	tsad^−/− (n = 11)
	mean ± SEM	mean ± SEM
Mean arterial blood pressure (mmHg)	85 ± 2	85 ± 5
Blood flow (ml/min g)
Pancreas caput	1.64 ± 0.34	2.52 ± 0.33
Pancreas cauda	1.38 ± 0.27	1.17 ± 0.27
Duodenum	3.19 ± 0.60	4.50 ± 0.96
Colon	2.34 ± 0.33	1.11 ± 0.28
Liver (hepatic artery)	0.02 ± 0.01	0.10 ± 0.03
Kidneys	4.38 ± 0.90	4.40 ± 1.07
Adrenal glands	17.57 ± 4.26	18.59 ± 4.95
Cerebrum	0.74 ± 0.11	1.49 ± 0.46
White adipose tissue	0.05 ± 0.01	0.01 ± 0.001
Lungs (= shunted blood)	0.07 ± 0.04	0.04 ± 0.01
Blood gases and pH^a
Blood pH	7.25 ± 0.03	7.28 ± 0.04
PCO₂ (kPa)	6.37 ± 0.32	5.06 ± 0.62
Total CO₂ (mmol/l)	22.6 ± 1.2	19.0 ± 1.9
PO₂ (kPa)	13.75 ± 0.46	11.85 ± 0.98
Oxygen saturation (%)	96.2 ± 0.9	94.1 ± 1.0
S-HCO₃^- (mmol/l)	21.0 ± 1.2	17.8 ± 1.6
S-Na⁺ (mmol/l)	144 ± 1	147 ± 1.0
S-K⁺ (mmol/l)	5.6 ± 0.2	4.7 ± 0.2
Base excess (mmol/l)	－6 ± 2	－8 ± 1.0
Hemoglobin (g/liter)	116 ± 4	112 ± 5

Strain	WT (n = 8)	tsad^−/− (n = 11)
	mean ± SEM	mean ± SEM
Mean arterial blood pressure (mmHg)	85 ± 2	85 ± 5
Blood flow (ml/min g)
Pancreas caput	1.64 ± 0.34	2.52 ± 0.33
Pancreas cauda	1.38 ± 0.27	1.17 ± 0.27
Duodenum	3.19 ± 0.60	4.50 ± 0.96
Colon	2.34 ± 0.33	1.11 ± 0.28
Liver (hepatic artery)	0.02 ± 0.01	0.10 ± 0.03
Kidneys	4.38 ± 0.90	4.40 ± 1.07
Adrenal glands	17.57 ± 4.26	18.59 ± 4.95
Cerebrum	0.74 ± 0.11	1.49 ± 0.46
White adipose tissue	0.05 ± 0.01	0.01 ± 0.001
Lungs (= shunted blood)	0.07 ± 0.04	0.04 ± 0.01
Blood gases and pHa
Blood pH	7.25 ± 0.03	7.28 ± 0.04
PCO₂ (kPa)	6.37 ± 0.32	5.06 ± 0.62
Total CO₂ (mmol/l)	22.6 ± 1.2	19.0 ± 1.9
PO₂ (kPa)	13.75 ± 0.46	11.85 ± 0.98
Oxygen saturation (%)	96.2 ± 0.9	94.1 ± 1.0
S-HCO₃^- (mmol/l)	21.0 ± 1.2	17.8 ± 1.6
S-Na⁺ (mmol/l)	144 ± 1	147 ± 1.0
S-K⁺ (mmol/l)	5.6 ± 0.2	4.7 ± 0.2
Base excess (mmol/l)	－6 ± 2	－8 ± 1.0
Hemoglobin (g/liter)	116 ± 4	112 ± 5

Both strains demonstrated slight anesthesia-induced hyperventilation (high PO₂, low PCO₂, low base excess, and low total CO₂). There were no significant differences between the groups.

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