Characterization of Cernunnos-deficient patients
| Patient ID | Age at sampling | T cell counts | B cell counts | Serum Ig | References | ||
| IgM | IgG | IgA | |||||
| yr | cells/µl | cells/µl | g/liter | g/liter | g/liter | ||
| P1 | 14 | 630↓ | 0↓ | 6.8↑ | 2.4↓ | <0.06↓ | P1 in Buck et al. (2006a) |
| P2 | 2 | 591↓ | 154↓ | 0.27↓ | 2.37↓ | <0.05↓ | P4 in Buck et al. (2006a) |
| P4 | 2 | 730↓ | 54↓ | 1.39 | <0.33↓ | <0.06↓ | P2 in Buck et al. (2006a) |
| P5 | 7 | 693↓ | 83↓ | 1.05 | 0.6↓ | 0.06↓ | P5 in Buck et al. (2006a) |
| P6 | 6 | 600↓ | 81↓ | 9.0↑ | <1.2↓ | <0.06↓ | This study |
| P7 | 2 | 1,260↓ | 38↓ | 0.53↓ | 1.4↓ | 0.13↓ | This study |
| P8 | 11 | 182↓ | 0↓ | 0.16↓ | 0.1↓ | <0.06↓ | This study |
| Patient ID | Age at sampling | T cell counts | B cell counts | Serum Ig | References | ||
| IgM | IgG | IgA | |||||
| yr | cells/µl | cells/µl | g/liter | g/liter | g/liter | ||
| P1 | 14 | 630↓ | 0↓ | 6.8↑ | 2.4↓ | <0.06↓ | P1 in Buck et al. (2006a) |
| P2 | 2 | 591↓ | 154↓ | 0.27↓ | 2.37↓ | <0.05↓ | P4 in Buck et al. (2006a) |
| P4 | 2 | 730↓ | 54↓ | 1.39 | <0.33↓ | <0.06↓ | P2 in Buck et al. (2006a) |
| P5 | 7 | 693↓ | 83↓ | 1.05 | 0.6↓ | 0.06↓ | P5 in Buck et al. (2006a) |
| P6 | 6 | 600↓ | 81↓ | 9.0↑ | <1.2↓ | <0.06↓ | This study |
| P7 | 2 | 1,260↓ | 38↓ | 0.53↓ | 1.4↓ | 0.13↓ | This study |
| P8 | 11 | 182↓ | 0↓ | 0.16↓ | 0.1↓ | <0.06↓ | This study |
Normal ranges for T and B cell counts and serum Ig levels have been described previously (Buck et al., 2006a). Values that are above or below the normal ranges are indicated by arrows. T cell counts are as follows: 2,300–5,400, 2 yr; 1,900–3,700, 6–7 yr; 1,400–3,300, 13–14 yr. B cell counts are as follows: 390–1,400, 2 yr; 110–570, 6–7 yr; 110–570, 13–14 yr. IgM levels are as follows: 0.72–1.6 g/liter, 2 yr; 0.6–1.75 g/liter, 6–7 yr; 0.4–1.8 g/liter, 13–14 yr. IgG levels are as follows: 5.2–10.8 g/liter, 2 yr; 5.7–13.2 g/liter, 6–7 yr; 6.4–14.2 g/liter, 13–14 yr. IgA levels are as follows: 0.36–1.65 g/liter, 2 yr; 0.65–2.4 g/liter, 6–7 yr; 0.52–2.2 g/liter, 13–14 yr (Buck et al., 2006a).