Table 1.

Characterization of Cernunnos-deficient patients

Patient ID Age at sampling T cell counts B cell counts Serum Ig References 
    IgM IgG IgA  
 yr cells/µl cells/µl g/liter g/liter g/liter  
P1 14 630↓ 0↓ 6.8↑ 2.4↓ <0.06↓ P1 in Buck et al. (2006a)  
P2 591↓ 154↓ 0.27↓ 2.37↓ <0.05↓ P4 in Buck et al. (2006a)  
P4 730↓ 54↓ 1.39 <0.33↓ <0.06↓ P2 in Buck et al. (2006a)  
P5 693↓ 83↓ 1.05 0.6↓ 0.06↓ P5 in Buck et al. (2006a)  
P6 600↓ 81↓ 9.0↑ <1.2↓ <0.06↓ This study 
P7 1,260↓ 38↓ 0.53↓ 1.4↓ 0.13↓ This study 
P8 11 182↓ 0↓ 0.16↓ 0.1↓ <0.06↓ This study 
Patient ID Age at sampling T cell counts B cell counts Serum Ig References 
    IgM IgG IgA  
 yr cells/µl cells/µl g/liter g/liter g/liter  
P1 14 630↓ 0↓ 6.8↑ 2.4↓ <0.06↓ P1 in Buck et al. (2006a)  
P2 591↓ 154↓ 0.27↓ 2.37↓ <0.05↓ P4 in Buck et al. (2006a)  
P4 730↓ 54↓ 1.39 <0.33↓ <0.06↓ P2 in Buck et al. (2006a)  
P5 693↓ 83↓ 1.05 0.6↓ 0.06↓ P5 in Buck et al. (2006a)  
P6 600↓ 81↓ 9.0↑ <1.2↓ <0.06↓ This study 
P7 1,260↓ 38↓ 0.53↓ 1.4↓ 0.13↓ This study 
P8 11 182↓ 0↓ 0.16↓ 0.1↓ <0.06↓ This study 

Normal ranges for T and B cell counts and serum Ig levels have been described previously (Buck et al., 2006a). Values that are above or below the normal ranges are indicated by arrows. T cell counts are as follows: 2,300–5,400, 2 yr; 1,900–3,700, 6–7 yr; 1,400–3,300, 13–14 yr. B cell counts are as follows: 390–1,400, 2 yr; 110–570, 6–7 yr; 110–570, 13–14 yr. IgM levels are as follows: 0.72–1.6 g/liter, 2 yr; 0.6–1.75 g/liter, 6–7 yr; 0.4–1.8 g/liter, 13–14 yr. IgG levels are as follows: 5.2–10.8 g/liter, 2 yr; 5.7–13.2 g/liter, 6–7 yr; 6.4–14.2 g/liter, 13–14 yr. IgA levels are as follows: 0.36–1.65 g/liter, 2 yr; 0.65–2.4 g/liter, 6–7 yr; 0.52–2.2 g/liter, 13–14 yr (Buck et al., 2006a).

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