Table 2.

Analysis of autoreactivity of LPS-induced B cell hybridomas from CB17-Igkm/h and MRL/lpr-Igkm/h mice

Self-reactivity MRL/lpr CB17 
 κ/κ κ κ/κ κ 
Chromatin 38% 11% 30% 12% 
Smith 19% 19% 21% 12% 
Hep2 38% 27% 51% 18% 
Overall Autoreactive 72% 46% 60% 33% 
Total tested 21 34 47 49 
Self-reactivity MRL/lpr CB17 
 κ/κ κ κ/κ κ 
Chromatin 38% 11% 30% 12% 
Smith 19% 19% 21% 12% 
Hep2 38% 27% 51% 18% 
Overall Autoreactive 72% 46% 60% 33% 
Total tested 21 34 47 49 

These hybridomas were randomly selected among those described in Table 1. All hybridoma were IgM except two that were IgG.

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