Table 1.

A summary of two independent MCA induction immunoediting experiments

Tumor group Growth in WT Growth in RAG−/− Growth in RAG−/−xγc−/− 
9 WT tumors into 87 WT or 22 RAG hosts (exp 1) 97% (84/87) 100% (22/22) ND 
15 RAG tumors into 120 WT or 7 into 15 RAG hosts (exp 1) 64% (77/120) 100% (15/15) ND 
17 RAGxγc tumors into 132 WT or 10 into 27 RAG hosts (exp 1) 46% (61/132) 100% (27/27) ND 
10 WT tumors into 35 WT or 21 RAGxγc hosts(exp 2) 100% (35/35) ND 100% (21/21) 
10 RAG tumors into 50 WT or 30 RAG hosts (exp 2) 60% (30/50) 100% (30/30) ND 
10 RAGxγc tumors into 50 WT or 30 RAGxγc hosts (exp 2) 30% (15/50) ND 100% (30/30) 
Tumor group Growth in WT Growth in RAG−/− Growth in RAG−/−xγc−/− 
9 WT tumors into 87 WT or 22 RAG hosts (exp 1) 97% (84/87) 100% (22/22) ND 
15 RAG tumors into 120 WT or 7 into 15 RAG hosts (exp 1) 64% (77/120) 100% (15/15) ND 
17 RAGxγc tumors into 132 WT or 10 into 27 RAG hosts (exp 1) 46% (61/132) 100% (27/27) ND 
10 WT tumors into 35 WT or 21 RAGxγc hosts(exp 2) 100% (35/35) ND 100% (21/21) 
10 RAG tumors into 50 WT or 30 RAG hosts (exp 2) 60% (30/50) 100% (30/30) ND 
10 RAGxγc tumors into 50 WT or 30 RAGxγc hosts (exp 2) 30% (15/50) ND 100% (30/30) 

A total of 71 MCA sarcoma cell lines were generated from the indicated mice and then transplanted into 474 WT, RAG−/−, or RAG2−/−x γc−/− mice, and tumor growth was monitored. Regressor frequencies from these experiments (1 and 2) are shown in Fig. 4. ND, not determined.

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