A summary of two independent MCA induction immunoediting experiments
| Tumor group | Growth in WT | Growth in RAG−/− | Growth in RAG−/−xγc−/− |
| 9 WT tumors into 87 WT or 22 RAG hosts (exp 1) | 97% (84/87) | 100% (22/22) | ND |
| 15 RAG tumors into 120 WT or 7 into 15 RAG hosts (exp 1) | 64% (77/120) | 100% (15/15) | ND |
| 17 RAGxγc tumors into 132 WT or 10 into 27 RAG hosts (exp 1) | 46% (61/132) | 100% (27/27) | ND |
| 10 WT tumors into 35 WT or 21 RAGxγc hosts(exp 2) | 100% (35/35) | ND | 100% (21/21) |
| 10 RAG tumors into 50 WT or 30 RAG hosts (exp 2) | 60% (30/50) | 100% (30/30) | ND |
| 10 RAGxγc tumors into 50 WT or 30 RAGxγc hosts (exp 2) | 30% (15/50) | ND | 100% (30/30) |
| Tumor group | Growth in WT | Growth in RAG−/− | Growth in RAG−/−xγc−/− |
| 9 WT tumors into 87 WT or 22 RAG hosts (exp 1) | 97% (84/87) | 100% (22/22) | ND |
| 15 RAG tumors into 120 WT or 7 into 15 RAG hosts (exp 1) | 64% (77/120) | 100% (15/15) | ND |
| 17 RAGxγc tumors into 132 WT or 10 into 27 RAG hosts (exp 1) | 46% (61/132) | 100% (27/27) | ND |
| 10 WT tumors into 35 WT or 21 RAGxγc hosts(exp 2) | 100% (35/35) | ND | 100% (21/21) |
| 10 RAG tumors into 50 WT or 30 RAG hosts (exp 2) | 60% (30/50) | 100% (30/30) | ND |
| 10 RAGxγc tumors into 50 WT or 30 RAGxγc hosts (exp 2) | 30% (15/50) | ND | 100% (30/30) |
A total of 71 MCA sarcoma cell lines were generated from the indicated mice and then transplanted into 474 WT, RAG−/−, or RAG2−/−x γc−/− mice, and tumor growth was monitored. Regressor frequencies from these experiments (1 and 2) are shown in Fig. 4. ND, not determined.
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