Summary of the clinical and genetic data for the patients
| Patient | Age at presentation | Origin | Clinical features of CMC | Cause of death (age/yr) | Autoimmunity | Genotype |
| A-I-1 | - | France | Nails | Not related to the disease (old age) | None | - |
| A-II-1 | - | France | Nails | Not related to the disease (old age) | None | - |
| A-III-1 | 1 mo | France | Nails, oral cavity, oropharynx, genital mucosa | None | WT/R274Q | |
| A-III-3 | - | France | Nails, oral cavity | Not related to the disease (40) | None | - |
| A-III-4 | - | France | Nails, oral cavity | None | - | |
| A-IV-1 | 1 mo | France | Nails, oral cavity, oropharynx | None | WT/R274Q | |
| B-II-1 | - | France | - | None | - | |
| B-III-2 | 3 yr | France | Skin, nails, oral cavity, oropharynx, genital mucosa | None | WT/K286I | |
| B-IV-1 | 5 yr | France & Congo | Skin, nails, oral cavity, oropharynx | None | WT/K286I | |
| B-IV-2 | 5 mo | France & Congo | Skin, nails, oral cavity, oropharynx | Cerebral aneurysm (8) | None | - |
| C-III-1 | - | Turkey | Nails, oral cavity, genital mucosa | Cerebral aneurysm (34) | Thyroid autoimmunity | WT/R274Q |
| C-IV-1 | - | Turkey | Nails, oral cavity | None | WT/R274Q | |
| D-II-1 | - | France | Nails, oral cavity, genital mucosa | - | - | |
| D-III-2 | 7 yr | France | Skin, oral cavity, oropharynx | None | WT/M202V | |
| D-IV-2 | 1 mo | France | Skin, nails, oropharynx | Thyroid autoimmunity | WT/M202V | |
| E-II-1 | 1 yr | Germany | Skin, oral cavity, oropharynx | Squamous cell carcinoma (54) | - | - |
| E-III-2 | 1 yr | Germany | Nails, oral cavity, oropharynx, genital mucosa | Thyroid autoimmunity | WT/C174R | |
| E-III-3 | 9 mo | Germany | Skin, nails, oral cavity, oropharynx, genital mucosa | Thyroid autoimmunity | WT/C174R | |
| E-IV-1 | 18 mo | Germany | Skin, oral cavity, oropharynx, genital mucosa | None | WT/C174R | |
| E-IV-2 | 2 yr | Germany | Skin, oral cavity, oropharynx | Thyroid autoimmunity | WT/C174R | |
| E-IV-4 | 2 yr | Germany | Skin, oral cavity, oropharynx, genital mucosa | None | WT/C174R | |
| E-IV-5 | 1 yr | Germany | Skin, nails, oral cavity, oropharynx | None | WT/C174R | |
| F-III-2 | 1 mo | Argentina | Nails, oral cavity, oropharynx, genital mucosa | - | WT/R274W | |
| F-IV-2 | 1 mo | Argentina | Skin, nails, oral cavity, oropharynx | - | WT/R274W | |
| F-IV-3 | 6 mo | Argentina | Nails, oral cavity, genital mucosa | - | WT/R274W | |
| G-II-1 | 3 mo | Ukrainian | Nails, skin, oral cavity, oropharynx, esophagus | None | WT/D165G | |
| H-I-2 | 1 yr | Japan | Skin, oropharynx, esophagus | - | WT/R274Q | |
| H-II-2 | 5 yr | Japan | Oral cavity, oropharynx | - | WT/R274Q | |
| I-II-3 | 9 mo | Mexico | Skin, nails, oral cavity, genital mucosa | None | WT/T288A | |
| J-I-2 | - | Switzerland | Oral cavity, oropharynx | None | WT/T288A | |
| J-II-2 | 3 mo | Switzerland | Oral cavity, oropharynx | - | WT/T288A | |
| K-II-2 | 11 mo | Switzerland | Nails, oral cavity, oropharynx | Thyroid autoimmunity | WT/Y170N | |
| L-I-2 | 7 yr | France | Skin, nails, oropharynx, esophagus | Thyroid autoimmunity | WT/R274Q | |
| L-II-1 | 1 mo | France | Skin, nails, oropharynx, esophagus | None | WT/R274Q | |
| M-II-2 | 6 mo | Germany | Skin, nails, oropharynx, genital mucosa | Thyroid autoimmunity | WT/D165H | |
| N-II-2 | 1 yr | Germany | Skin, nails, oropharynx | Squamous cell carcinoma (54) | None | WT/R274W |
| O-II-1 | 18 mo | Germany | Oral cavity, oropharynx | None | WT/M202I | |
| P-I-1 | 1 yr | Israel | Oropharynx, genital mucosa | Not related to the disease (46) | None | - |
| P-II-1 | <2 yr | Israel | Skin, nails, oropharynx | None | WT/A267V | |
| P-II-2 | <2 yr | Israel | Skin, nails, oropharynx | None | WT/A267V | |
| Q-II-1 | 1 mo | France | Skin, oral cavity, oropharynx, genital mucosa | None | WT/R274W | |
| R-I-1 | 4 yr | France | Skin, nails, oropharynx | Squamous cell carcinoma (55) | None | - |
| R-II-1 | 18 mo | France | Lips, oropharynx | None | WT/M202V | |
| S-I-2 | 6 mo | France | Skin, oral cavity, oropharynx | Systemic lupus erythematosus | WT/M202I | |
| S-II-2 | 1 yr | France | Nails | None | - | |
| S-II-3 | 1 mo | France | Skin, oropharynx | None | WT/M202I | |
| T-II-3 | 1 yr | Germany | Skin, nails, oropharynx | Squamous cell carcinoma (41) | None | WT/Q271P |
| Patient | Age at presentation | Origin | Clinical features of CMC | Cause of death (age/yr) | Autoimmunity | Genotype |
| A-I-1 | - | France | Nails | Not related to the disease (old age) | None | - |
| A-II-1 | - | France | Nails | Not related to the disease (old age) | None | - |
| A-III-1 | 1 mo | France | Nails, oral cavity, oropharynx, genital mucosa | None | WT/R274Q | |
| A-III-3 | - | France | Nails, oral cavity | Not related to the disease (40) | None | - |
| A-III-4 | - | France | Nails, oral cavity | None | - | |
| A-IV-1 | 1 mo | France | Nails, oral cavity, oropharynx | None | WT/R274Q | |
| B-II-1 | - | France | - | None | - | |
| B-III-2 | 3 yr | France | Skin, nails, oral cavity, oropharynx, genital mucosa | None | WT/K286I | |
| B-IV-1 | 5 yr | France & Congo | Skin, nails, oral cavity, oropharynx | None | WT/K286I | |
| B-IV-2 | 5 mo | France & Congo | Skin, nails, oral cavity, oropharynx | Cerebral aneurysm (8) | None | - |
| C-III-1 | - | Turkey | Nails, oral cavity, genital mucosa | Cerebral aneurysm (34) | Thyroid autoimmunity | WT/R274Q |
| C-IV-1 | - | Turkey | Nails, oral cavity | None | WT/R274Q | |
| D-II-1 | - | France | Nails, oral cavity, genital mucosa | - | - | |
| D-III-2 | 7 yr | France | Skin, oral cavity, oropharynx | None | WT/M202V | |
| D-IV-2 | 1 mo | France | Skin, nails, oropharynx | Thyroid autoimmunity | WT/M202V | |
| E-II-1 | 1 yr | Germany | Skin, oral cavity, oropharynx | Squamous cell carcinoma (54) | - | - |
| E-III-2 | 1 yr | Germany | Nails, oral cavity, oropharynx, genital mucosa | Thyroid autoimmunity | WT/C174R | |
| E-III-3 | 9 mo | Germany | Skin, nails, oral cavity, oropharynx, genital mucosa | Thyroid autoimmunity | WT/C174R | |
| E-IV-1 | 18 mo | Germany | Skin, oral cavity, oropharynx, genital mucosa | None | WT/C174R | |
| E-IV-2 | 2 yr | Germany | Skin, oral cavity, oropharynx | Thyroid autoimmunity | WT/C174R | |
| E-IV-4 | 2 yr | Germany | Skin, oral cavity, oropharynx, genital mucosa | None | WT/C174R | |
| E-IV-5 | 1 yr | Germany | Skin, nails, oral cavity, oropharynx | None | WT/C174R | |
| F-III-2 | 1 mo | Argentina | Nails, oral cavity, oropharynx, genital mucosa | - | WT/R274W | |
| F-IV-2 | 1 mo | Argentina | Skin, nails, oral cavity, oropharynx | - | WT/R274W | |
| F-IV-3 | 6 mo | Argentina | Nails, oral cavity, genital mucosa | - | WT/R274W | |
| G-II-1 | 3 mo | Ukrainian | Nails, skin, oral cavity, oropharynx, esophagus | None | WT/D165G | |
| H-I-2 | 1 yr | Japan | Skin, oropharynx, esophagus | - | WT/R274Q | |
| H-II-2 | 5 yr | Japan | Oral cavity, oropharynx | - | WT/R274Q | |
| I-II-3 | 9 mo | Mexico | Skin, nails, oral cavity, genital mucosa | None | WT/T288A | |
| J-I-2 | - | Switzerland | Oral cavity, oropharynx | None | WT/T288A | |
| J-II-2 | 3 mo | Switzerland | Oral cavity, oropharynx | - | WT/T288A | |
| K-II-2 | 11 mo | Switzerland | Nails, oral cavity, oropharynx | Thyroid autoimmunity | WT/Y170N | |
| L-I-2 | 7 yr | France | Skin, nails, oropharynx, esophagus | Thyroid autoimmunity | WT/R274Q | |
| L-II-1 | 1 mo | France | Skin, nails, oropharynx, esophagus | None | WT/R274Q | |
| M-II-2 | 6 mo | Germany | Skin, nails, oropharynx, genital mucosa | Thyroid autoimmunity | WT/D165H | |
| N-II-2 | 1 yr | Germany | Skin, nails, oropharynx | Squamous cell carcinoma (54) | None | WT/R274W |
| O-II-1 | 18 mo | Germany | Oral cavity, oropharynx | None | WT/M202I | |
| P-I-1 | 1 yr | Israel | Oropharynx, genital mucosa | Not related to the disease (46) | None | - |
| P-II-1 | <2 yr | Israel | Skin, nails, oropharynx | None | WT/A267V | |
| P-II-2 | <2 yr | Israel | Skin, nails, oropharynx | None | WT/A267V | |
| Q-II-1 | 1 mo | France | Skin, oral cavity, oropharynx, genital mucosa | None | WT/R274W | |
| R-I-1 | 4 yr | France | Skin, nails, oropharynx | Squamous cell carcinoma (55) | None | - |
| R-II-1 | 18 mo | France | Lips, oropharynx | None | WT/M202V | |
| S-I-2 | 6 mo | France | Skin, oral cavity, oropharynx | Systemic lupus erythematosus | WT/M202I | |
| S-II-2 | 1 yr | France | Nails | None | - | |
| S-II-3 | 1 mo | France | Skin, oropharynx | None | WT/M202I | |
| T-II-3 | 1 yr | Germany | Skin, nails, oropharynx | Squamous cell carcinoma (41) | None | WT/Q271P |
None of the patients displays autoantibodies against IL-17A, IL-17F, and IL-22. -, unknown