Table I.

STAT3 somatic mutations identified in inflammatory hepatocellular tumors

Tumors Nucleotide change Amino acid change Mutant ID 
CHC341T T233>G L78>R L78 
CHC379T G1504>T D502>Y D502 
 A1972>T; G1974>T K658>Y K658 
CHC574T G496>C E166>Q E166 
CHC966T A1919>T Y640>F Y640 
CHC1021T T1969_G1980dup Y657_M660dup Y657 
CHC1351T C1968>T; 1969_1970insTTT G656_Y657insF G656 

Codons and mutated nucleotides are numbered according to STAT3 cDNA open reading frame.

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