Lymphocyte population in CIN85 bKO mice
| Genotype | BM (×106) | Spleen (×106) | PerC (×105) | |||||||
| Pro/Pre | Immature | Recirculate | T1 | T2 | T3 | FO | MZ | T cells | B-1a | |
| Control | 8.9 ± 2.8 | 3.7 ± 1.4 | 3.4 ± 0.3 | 1.7 ± 0.3 | 3.6 ± 0.6 | 3.4 ± 1.0 | 24.6 ± 2.6 | 2.5 ± 0.5 | 21.5 ± 2.4 | 3.0 ± 0.5 |
| bKO | 8.9 ± 2.5 | 2.6 ± 1.0 | 2.3 ± 0.3 | 1.9 ± 0.3 | 2.8 ± 0.6 | 2.7 ± 0.8 | 19.5 ± 1.9 | 2.8 ± 0.5 | 19.4 ± 1.8 | 0.4 ± 0.2 |
| Genotype | BM (×106) | Spleen (×106) | PerC (×105) | |||||||
| Pro/Pre | Immature | Recirculate | T1 | T2 | T3 | FO | MZ | T cells | B-1a | |
| Control | 8.9 ± 2.8 | 3.7 ± 1.4 | 3.4 ± 0.3 | 1.7 ± 0.3 | 3.6 ± 0.6 | 3.4 ± 1.0 | 24.6 ± 2.6 | 2.5 ± 0.5 | 21.5 ± 2.4 | 3.0 ± 0.5 |
| bKO | 8.9 ± 2.5 | 2.6 ± 1.0 | 2.3 ± 0.3 | 1.9 ± 0.3 | 2.8 ± 0.6 | 2.7 ± 0.8 | 19.5 ± 1.9 | 2.8 ± 0.5 | 19.4 ± 1.8 | 0.4 ± 0.2 |
Mean cell numbers of each population were calculated on the basis of total cell number and the percentages obtained from the flow cytometric analysis. Data are shown as mean ± SE (control, n = 7; bKO, n = 7). Pro, pro–B cells; Pre, pre–B cells, Immature, immature B cells; Recirculate, recirculating B cells; T1, T1 B cells; T2, T2 B cells; T3, T3 B cells; FO, FO B cells; MZ, MZ B cells; PerC, peritoneal cavity.