Table II.

Contacts of Hy.1B11 TCR with the MBP85-99 peptide

CDR TCR residue Residue of peptide Number of contacts 
Contacts to peptide by TCR-α chain  
    CDR1α S28# P-3 Asn 
    CDR3α F95 P2 His 15 
    CDR3α F95 P3 Phe 
    CDR3α F95* P5 Lys 
    CDR3α E98 P5 Lys 
Contacts to peptide by TCR-β chain  
    CDR1β Thr28 P8 Val 
    CDR2β Gln48 P8 Val 
    CDR2β Gly49 P8 Val 
CDR TCR residue Residue of peptide Number of contacts 
Contacts to peptide by TCR-α chain  
    CDR1α S28# P-3 Asn 
    CDR3α F95 P2 His 15 
    CDR3α F95 P3 Phe 
    CDR3α F95* P5 Lys 
    CDR3α E98 P5 Lys 
Contacts to peptide by TCR-β chain  
    CDR1β Thr28 P8 Val 
    CDR2β Gln48 P8 Val 
    CDR2β Gly49 P8 Val 

Putative hydrogen bond to peptide sidechain (*) or to peptide backbone (#).

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