Logistic regression analysis showing independent variables associated with poor functional outcome at 3 mo (mRS > 2) after stroke
| Variable | Ischemic stroke | ICH | ||||
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age | 1.05 | 1.00–1.09 | 0.013 | 1.07 | 0.99–1.15 | 0.059 |
| Diabetes | 0.70 | 0.10–4.86 | 0.720 | |||
| Blood glucose | 0.99 | 0.97–1.01 | 0.720 | |||
| ICH volume | 0.99 | 0.95–1.03 | 0.745 | |||
| Edema volume | 1.02 | 0.97–1.08 | 0.334 | |||
| Ventricular Extension | 4.82 | 0.69–33.5 | 0.112 | |||
| NIHSS on admission | 1.33 | 1.20–1.48 | <0.0001 | 1.42 | 1.16–1.72 | <0.0001 |
| Infarct volume | 1.01 | 1.00–1.03 | 0.035 | |||
| END | 15.29 | 2.58–90.62 | 0.003 | |||
| Arg/Arg genotype | 3.89 | 1.63–9.28 | 0.002 | 360.7 | 31.5–4,132.1 | <0.0001 |
| Variable | Ischemic stroke | ICH | ||||
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age | 1.05 | 1.00–1.09 | 0.013 | 1.07 | 0.99–1.15 | 0.059 |
| Diabetes | 0.70 | 0.10–4.86 | 0.720 | |||
| Blood glucose | 0.99 | 0.97–1.01 | 0.720 | |||
| ICH volume | 0.99 | 0.95–1.03 | 0.745 | |||
| Edema volume | 1.02 | 0.97–1.08 | 0.334 | |||
| Ventricular Extension | 4.82 | 0.69–33.5 | 0.112 | |||
| NIHSS on admission | 1.33 | 1.20–1.48 | <0.0001 | 1.42 | 1.16–1.72 | <0.0001 |
| Infarct volume | 1.01 | 1.00–1.03 | 0.035 | |||
| END | 15.29 | 2.58–90.62 | 0.003 | |||
| Arg/Arg genotype | 3.89 | 1.63–9.28 | 0.002 | 360.7 | 31.5–4,132.1 | <0.0001 |
Patients were admitted at the University Hospital of Santiago de Compostela (Galicia, Spain; cohort 1). OR and their 95% CI were calculated to demonstrate the independent association between poor prognosis and Arg/Arg genotype. Analysis of variables from cohort 2 (Catalonia, Spain) is shown in Table S3.