Table I.

Clinical information of 5 AHI patients

Subjectsa Age (gender) Days since infectionb Viral load copies/ml CD4 count cells /µl Plasma anti–HIV-1 gp41 Fiebig stagec 
  EIA Western blot IgM IgG IgA 
065-0 35 (M) 17 391 269 Neg. Neg. Neg. Neg. Neg. 2/1 
068-9d 37 (M) 30 258 611 Pos. Neg. Pos. Neg. Neg. 
681-7 42 (M) 20 5,900,000 230 Neg. Neg. Neg. Neg. Neg. 2/1 
684-6 32 (M) 20 10,925,000 225 Pos. Neg. Pos. Pos. Pos. 
001-4 26 (M) 20 4,700,000 165 Pos. Ind. Pos. Pos. Pos. 
Subjectsa Age (gender) Days since infectionb Viral load copies/ml CD4 count cells /µl Plasma anti–HIV-1 gp41 Fiebig stagec 
  EIA Western blot IgM IgG IgA 
065-0 35 (M) 17 391 269 Neg. Neg. Neg. Neg. Neg. 2/1 
068-9d 37 (M) 30 258 611 Pos. Neg. Pos. Neg. Neg. 
681-7 42 (M) 20 5,900,000 230 Neg. Neg. Neg. Neg. Neg. 2/1 
684-6 32 (M) 20 10,925,000 225 Pos. Neg. Pos. Pos. Pos. 
001-4 26 (M) 20 4,700,000 165 Pos. Ind. Pos. Pos. Pos. 

EIA, enzyme immunoassay; Neg., negative; Pos., positive; Ind., indeterminate, as one or more bands are present but the blot did not meet the criteria for positive in that at least one of gp160 and/or gp120, gp41, or gp24 must be present.

a

Patient no. 068-9 received ART for 7 d after exposure, 21 d before blood and bone marrow samples were obtained from.

b

Days since infection were determined by clinical information of last contact or by days from onset of AHI symptoms. All patients had admitted to hospitals of recent contact except 684-6, who had AHI symptoms and had negative Western blot analysis with high plasma viral load.

c

Based on description reported by Fiebig et al (2003).

d

All five subjects were quickly placed on antiretroviral therapy soon after diagnosis and consequently none developed detectable autologous or heterologous neutralizing antibodies during up to 2 yr of follow up (unpublished data).

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