Table I.
Effect of CD8 deletion on Vα14
i
NKT thymocyte and Vβ repertoire
Strain
Vα14
i
NKT cells that express Vβ2
Vα14
i
NKT cells that express Vβ7
Vα14
i
NKT cells that express Vβ8.1/8.2
%
%
%
C57BL/6 (
n
= 6)
14 ± 4
15 ± 4
70 ± 2
Cd8a
−/−
(
n
= 6)
11 ± 1
16 ± 3
67 ± 5
Fold change in KO versus WT
0.8
1.1
1.0
Strain
Vα14
i
NKT cells that express Vβ2
Vα14
i
NKT cells that express Vβ7
Vα14
i
NKT cells that express Vβ8.1/8.2
%
%
%
C57BL/6 (
n
= 6)
14 ± 4
15 ± 4
70 ± 2
Cd8a
−/−
(
n
= 6)
11 ± 1
16 ± 3
67 ± 5
Fold change in KO versus WT
0.8
1.1
1.0
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