Blood glucose (BG) level at the onset of hyperglycemia and at termination of treatment regimena
| Mouse ID . | Age at onset of hyperglycemia (wk) . | Blood glucose level before treatment (mg/dl)b . | Blood glucose level after termination of treatment (mg/dl)c . |
|---|---|---|---|
| 15-wk treatment regimen | |||
| 106.1 | 30 | 161 | 133 |
| 106.7 | 30 | 165 | 113 |
| 119.2 | 30 | 180 | 285d |
| 119.8 | 26 | 182 | 112 |
| 119.9 | 28 | 165 | 128 |
| 190.1 | 12 | 250 | 118 |
| 191.2 | 18 | 179 | 99 |
| 192.2 | 26 | 212 | 134d |
| 192.3 | 16 | 160 | 308d |
| 196.1 | 22 | 222 | 150d |
| 25-wk treatment schedule | |||
| 220.1 | 26 | 160 | 135 |
| 221.12 | 24 | 174 | 120 |
| 206.2 | 24 | 231 | 121 |
| 203.1 | 24 | 181 | 110 |
| 232.3 | 20 | 173 | 140 |
| 236.6 | 14 | 185 | 116 |
| 225.9 | 26 | 163 | 120 |
| 237.8 | 20 | 250 | 130 |
| 227.7 | 28 | 180 | 137 |
| 244.4 | 16 | 171 | 123 |
| Mouse ID . | Age at onset of hyperglycemia (wk) . | Blood glucose level before treatment (mg/dl)b . | Blood glucose level after termination of treatment (mg/dl)c . |
|---|---|---|---|
| 15-wk treatment regimen | |||
| 106.1 | 30 | 161 | 133 |
| 106.7 | 30 | 165 | 113 |
| 119.2 | 30 | 180 | 285d |
| 119.8 | 26 | 182 | 112 |
| 119.9 | 28 | 165 | 128 |
| 190.1 | 12 | 250 | 118 |
| 191.2 | 18 | 179 | 99 |
| 192.2 | 26 | 212 | 134d |
| 192.3 | 16 | 160 | 308d |
| 196.1 | 22 | 222 | 150d |
| 25-wk treatment schedule | |||
| 220.1 | 26 | 160 | 135 |
| 221.12 | 24 | 174 | 120 |
| 206.2 | 24 | 231 | 121 |
| 203.1 | 24 | 181 | 110 |
| 232.3 | 20 | 173 | 140 |
| 236.6 | 14 | 185 | 116 |
| 225.9 | 26 | 163 | 120 |
| 237.8 | 20 | 250 | 130 |
| 227.7 | 28 | 180 | 137 |
| 244.4 | 16 | 171 | 123 |
The results illustrated in this table were from the mice treated with either the 15- or 25-wk Ig-GAD2 treatment regimen and described in Fig. 2. The hyperglycemia onset represent the week during which the mice showed, for the first time, a blood glucose level of 160–250 mg/dl.
Blood glucose level obtained the second week of hyperglycemia.
Blood glucose level obtained at the termination of treatment regimen.
Mice that became diabetic before or within 7 wk of treatment termination.