Table II.

Frequent Arg mutations at AGC and AGT codons in V genes

V genes Arg mutations at AGC Arg mutations at AGT AGC codons in V genesa AGT codons in V genes AGC+AGT CDR1 and CDR2 AGC+AGT FR1 and FR2 
 % % % % % % 
VH 41.7 16.7 3.7 2.0 10.8 1.8 
Vκ 38.9 33.3 3.0 6.1 17.9 1.9 
V genes Arg mutations at AGC Arg mutations at AGT AGC codons in V genesa AGT codons in V genes AGC+AGT CDR1 and CDR2 AGC+AGT FR1 and FR2 
 % % % % % % 
VH 41.7 16.7 3.7 2.0 10.8 1.8 
Vκ 38.9 33.3 3.0 6.1 17.9 1.9 

This table refers to anti-chromatin antibodies in this study.

a

AGC and AGT codon usage among 52,926 mouse genomic codons is 1.6 and 0.92%, respectively (GenBank: http://www.kazusa.or.jp/codon/cgi-bin/showcodon.cgi?species=10092).

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