Table 2.
Parameters of sum of exponential fits for recovery curves
Channel variantCAfτfAsτs
   ms  ms 
200-ms pulse      
DIII-LFS 0.967 ± 0.006 0.978 ± 0.049 4.443 ± 0.615 0.183 ± 0.019 83.5 ± 17.1 
DIII-N1325S 0.990 ± 0.005 1.042 ± 0.065 3.237 ± 0.550 0.172 ± 0.026 22.9 ± 6.3 
DIII-A1330P 0.989 ± 0.004 1.006 ± 0.019 3.952 ± 0.254 0.141 ± 0.034 44.0 ± 5.6 
DIII-N1659A 0.995 ± 0.005 0.528 ± 0.165 1.906 ± 0.438 0.115 ± 0.010 44.3 ± 15.0 
DIII-IQM 0.998 ± 0.001 0.532 ± 0.063 1.472 ± 0.144 0.069 ± 0.011 24.5 ± 6.3 
10-ms pulse      
DIII-LFS 0.991 ± 0.003 1.000 ± 0.034 5.346 ± 0.455 0.087 ± 0.008 64.6 ± 10.5 
DIII-N1325S 0.993 ± 0.007 0.983 ± 0.019 5.073 ± 0.406 0.114 ± 0.008 52.0 ± 10.1 
DIII-A1330P 0.993 ± 0.001 1.121 ± 0.077 2.322 ± 0.186 0.114 ± 0.007 15.6 ± 1.6 
DIII-N1659A 0.989 ± 0.011 0.493 ± 0.153 0.900 ± 0.485 0.035 ± 0.020 32.1 ± 17.9 
Channel variantCAfτfAsτs
   ms  ms 
200-ms pulse      
DIII-LFS 0.967 ± 0.006 0.978 ± 0.049 4.443 ± 0.615 0.183 ± 0.019 83.5 ± 17.1 
DIII-N1325S 0.990 ± 0.005 1.042 ± 0.065 3.237 ± 0.550 0.172 ± 0.026 22.9 ± 6.3 
DIII-A1330P 0.989 ± 0.004 1.006 ± 0.019 3.952 ± 0.254 0.141 ± 0.034 44.0 ± 5.6 
DIII-N1659A 0.995 ± 0.005 0.528 ± 0.165 1.906 ± 0.438 0.115 ± 0.010 44.3 ± 15.0 
DIII-IQM 0.998 ± 0.001 0.532 ± 0.063 1.472 ± 0.144 0.069 ± 0.011 24.5 ± 6.3 
10-ms pulse      
DIII-LFS 0.991 ± 0.003 1.000 ± 0.034 5.346 ± 0.455 0.087 ± 0.008 64.6 ± 10.5 
DIII-N1325S 0.993 ± 0.007 0.983 ± 0.019 5.073 ± 0.406 0.114 ± 0.008 52.0 ± 10.1 
DIII-A1330P 0.993 ± 0.001 1.121 ± 0.077 2.322 ± 0.186 0.114 ± 0.007 15.6 ± 1.6 
DIII-N1659A 0.989 ± 0.011 0.493 ± 0.153 0.900 ± 0.485 0.035 ± 0.020 32.1 ± 17.9 

As described in the Materials and methods section, time dependence of recovery saw fit using a sum of exponentials with the following equation: fraction recovered y = C − Af*exp(−t/τf) − As*exp(−t/τs). Recovery after 10- and 200-ms depolarizing pulses are both shown here. Mean ± SEM of each parameter for sets of three to seven cells are shown.

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