Model parameters that were varied to simulate the effects of forskolin on flash response (Fig. 8)
| Parameter | Cell 1 | Cell 2 | ||
| NR | forsk | NR | forsk | |
| IcGdark (pA) | 17.8 | 19 | 18 | 18 |
| fCa | 0.15 | 0.211 | 0.15 | 0.19 |
| Cad (M) | 5 × 10−7 | 7 × 10−7 | 5 × 10−7 | 6.62 × 10−7 |
| αmax (M · s−1) | 5.87 × 10−6 | 4.66 × 10−6 | 5.66 × 10−6 | 4.91 × 10−6 |
| βdark (M · s−1) | 1.659 × 10−6 | 0.826 × 10−6 | 1.6 × 10−6 | 0.833 × 10−6 |
| kE (s−1) | 3.6 | 2.6 | 1.81 | 1.45 |
| τA (s) | 2 | 2.6 | 2.5 | 2.7 |
| Parameter | Cell 1 | Cell 2 | ||
| NR | forsk | NR | forsk | |
| IcGdark (pA) | 17.8 | 19 | 18 | 18 |
| fCa | 0.15 | 0.211 | 0.15 | 0.19 |
| Cad (M) | 5 × 10−7 | 7 × 10−7 | 5 × 10−7 | 6.62 × 10−7 |
| αmax (M · s−1) | 5.87 × 10−6 | 4.66 × 10−6 | 5.66 × 10−6 | 4.91 × 10−6 |
| βdark (M · s−1) | 1.659 × 10−6 | 0.826 × 10−6 | 1.6 × 10−6 | 0.833 × 10−6 |
| kE (s−1) | 3.6 | 2.6 | 1.81 | 1.45 |
| τA (s) | 2 | 2.6 | 2.5 | 2.7 |
IcGdark, dark current; fCa, fraction of ROS current carried by Ca2+; Cad, dark concentration of free Ca2+; αmax, maximum rate of cGMP synthesis achieved at zero Ca2+; βdark, rate of dark cGMP hydrolysis; kE, rate constant of PDE* turnoff; τA, time constant of arrestin binding to phosphorylated rhodopsin.