Table 1. Results of linear least-squares... | Rockefeller University Press

Table 1.

Results of linear least-squares best fits of Δ[Ca_T]_SR,model to Δ[Ca_T]_SR

1	2	3	4	5	6	7	8
Fiber	K_CB	n	[CaIB]_max	f_CB,R	[CaIB]_R	r	q
	mM		mM		mM
Case 1: [Ca²⁺]_SR,R = 0.6656 mM, K_app = 2.6 mM
724011	0.75	3.79	38.2	0.389	14.9	24.9	51.7
211021	0.95	2.29	58.5	0.304	17.8	28.6	42.1
423021	0.64	2.86	35.5	0.528	18.7	30.1	38.0
Mean	0.78	2.98	44.0	0.407	17.1	27.9	43.9
SEM	0.09	0.44	7.3	0.065	1.1	1.5	4.1
Case 2: [Ca²⁺]_SR,R = 0.26 mM, K_app = 1.0 mM
724011	0.30	3.66	40.8	0.372	15.2	63.3	134.2
211021	0.38	2.24	60.7	0.299	18.2	73.1	109.6
423021	0.25	2.83	36.2	0.528	19.1	76.9	98.1
Mean	0.31	2.91	45.9	0400	17.5	71.1	114.0
SEM	0.04	0.41	7.5	0.068	1.2	4.1	10.6
Case 3: [Ca²⁺]_SR,R = 2.35 mM, K_app = 9.1 mM
724011	2.34	4.68	26.6	0.505	13.4	7.1	13.2
211021	2.95	2.51	45.0	0.361	16.2	8.2	11.1
423021	2.15	3.12	30.3	0.569	17.2	8.6	9.9
Mean	2.48	3.44	34.0	0.478	15.6	8.0	11.4
SEM	0.24	0.65	5.6	0.062	1.1	0.4	1.0
Case 4: [Ca²⁺]_SR,R = 3.0 mM, K_app = 2.6 mM
724011	2.58	3.44	20.2	0.629	12.7	5.6	5.4
211021	2.55	2.05	26.7	0.583	15.5	6.4	4.4
423021	2.08	2.48	23.2	0.713	16.5	6.7	3.9
Mean	2.40	2.66	23.4	0.642	14.9	6.2	4.6
SEM	0.16	0.41	1.9	0.038	1.1	0.3	0.4

1	2	3	4	5	6	7	8
Fiber	K_CB	n	[CaIB]_max	f_CB,R	[CaIB]_R	r	q
	mM		mM		mM
Case 1: [Ca²⁺]_SR,R = 0.6656 mM, K_app = 2.6 mM
724011	0.75	3.79	38.2	0.389	14.9	24.9	51.7
211021	0.95	2.29	58.5	0.304	17.8	28.6	42.1
423021	0.64	2.86	35.5	0.528	18.7	30.1	38.0
Mean	0.78	2.98	44.0	0.407	17.1	27.9	43.9
SEM	0.09	0.44	7.3	0.065	1.1	1.5	4.1
Case 2: [Ca²⁺]_SR,R = 0.26 mM, K_app = 1.0 mM
724011	0.30	3.66	40.8	0.372	15.2	63.3	134.2
211021	0.38	2.24	60.7	0.299	18.2	73.1	109.6
423021	0.25	2.83	36.2	0.528	19.1	76.9	98.1
Mean	0.31	2.91	45.9	0400	17.5	71.1	114.0
SEM	0.04	0.41	7.5	0.068	1.2	4.1	10.6
Case 3: [Ca²⁺]_SR,R = 2.35 mM, K_app = 9.1 mM
724011	2.34	4.68	26.6	0.505	13.4	7.1	13.2
211021	2.95	2.51	45.0	0.361	16.2	8.2	11.1
423021	2.15	3.12	30.3	0.569	17.2	8.6	9.9
Mean	2.48	3.44	34.0	0.478	15.6	8.0	11.4
SEM	0.24	0.65	5.6	0.062	1.1	0.4	1.0
Case 4: [Ca²⁺]_SR,R = 3.0 mM, K_app = 2.6 mM
724011	2.58	3.44	20.2	0.629	12.7	5.6	5.4
211021	2.55	2.05	26.7	0.583	15.5	6.4	4.4
423021	2.08	2.48	23.2	0.713	16.5	6.7	3.9
Mean	2.40	2.66	23.4	0.642	14.9	6.2	4.6
SEM	0.16	0.41	1.9	0.038	1.1	0.3	0.4

Column 1 gives the fiber reference. See text for an explanation of the values in columns 2–8. For reference 724011, 211021, and 423021, respectively, the ranges of values of k for proton loss (Eqs. S1 and S2 and associated supplemental text) used to impose the constraints of matched slopes and values of the [Ca_T]_SR and [Ca_T]_SR,model signals for cases 1–4 were 0.8–1.7, 8.3–8.6, and 10.9–11.5 × 10⁻⁵ pH units/ms. The corresponding ranges of pH_min were −0.187 to −0.190, −0.215 to −0.216, and −0.222 to −0.225. Additional details for these fibers are given in the legends (for Fibers 724011, 211021, and 423021, respectively) of Tables 2 and 3 of Pape et al. (2007).

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