Table 1. Steady-state intrinsic gating... | Rockefeller University Press

Table 1.

Steady-state intrinsic gating parameters

Channels α_F380Y	L₀	P-value	z_L	P-value (approximately)	ΔΔG	n
	e⁻²		e₀		kcal/mol
No β1	6.6 ± 0.9	<0.001	0.16 ± 0.01	0.5		5
WT β1	4.3 ± 1.9^a	NA	0.20 ± 0.05	NA	1.62	7
β1_Y105A	1.9 ± 0.4	<0.01	0.21 ± 0.02	0.8	0.74	8
β1_I106A	4.4 ± 1.1	<0.01	0.24 ± 0.04	0.5	0.39	8
β1_Y74A	2.5 ± 0.5	<0.01	0.20 ± 0.02	0.7	0.58	9
β1_Y74AY105A	2.0 ± 0.3	<0.001	0.21 ± 0.02	0.9	0.71	9

Channels α_F380Y	L₀	P-value	z_L	P-value (approximately)	ΔΔG	n
	e⁻²		e₀		kcal/mol
No β1	6.6 ± 0.9	<0.001	0.16 ± 0.01	0.5		5
WT β1	4.3 ± 1.9^a	NA	0.20 ± 0.05	NA	1.62	7
β1_Y105A	1.9 ± 0.4	<0.01	0.21 ± 0.02	0.8	0.74	8
β1_I106A	4.4 ± 1.1	<0.01	0.24 ± 0.04	0.5	0.39	8
β1_Y74A	2.5 ± 0.5	<0.01	0.20 ± 0.02	0.7	0.58	9
β1_Y74AY105A	2.0 ± 0.3	<0.001	0.21 ± 0.02	0.9	0.71	9

NA, not applicable.

e−3.