Table 2. Comparison of free energy... | Rockefeller University Press

Table 2.

Comparison of free energy estimates from kinetic models and median method

Channel	$K_{1}^{0}$	z₁	$K_{2}^{0}$	z₂	$K_{L}^{0}$	z_L	$Δ {\bar{G}}_{C} = - R T \ln {{(K_{1}^{0} K_{2}^{0})}^{4} K_{L}^{0}}$	Q_max	V_m	Q_maxFV_m
							kcal/mol		mV	kcal/mol
Sh-IR	3	1.8	132.07	1.4	12	0.4	−15.58	13.2	−46.8	−14.19
ILT	74.667	1.7	466.667	1.3	0.0143	1.8	−22.17	13.8	−67.4	−21.37

Channel	$K_{1}^{0}$	z₁	$K_{2}^{0}$	z₂	$K_{L}^{0}$	z_L	$Δ {\bar{G}}_{C} = - R T \ln {{(K_{1}^{0} K_{2}^{0})}^{4} K_{L}^{0}}$	Q_max	V_m	Q_maxFV_m
							kcal/mol		mV	kcal/mol
Sh-IR	3	1.8	132.07	1.4	12	0.4	−15.58	13.2	−46.8	−14.19
ILT	74.667	1.7	466.667	1.3	0.0143	1.8	−22.17	13.8	−67.4	−21.37

The table lists the parameters of the ZHA model for the Sh-IR channel and the ILT mutant. V_m value for the ILT mutant was calculated from the QV curve, generated using the model parameters published previously (Ledwell and Aldrich, 1999; Fig. 2). The Q_max values used in both cases are those specified in the ZHA model.

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