Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 1 mM MgADP
| Solution | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Control | 0.34 ± 0.01 | 0.934 ± 0.011 | 7.4 ± 1.8 | 0.022 ± 0.008 | 38 ± 8 | 0.035 ± 0.006 | 306 ± 132 | 0.008 ± 0.005 |
| 1 mM MgADP | 0.36 ± 0.01 | 0.988 ± 0.002 | 4.0 ± 1.0 | 0.005 ± 0.002 | 16.8 ± 2.6 | 0.007 ± 0.001 | np | np |
| Solution | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Control | 0.34 ± 0.01 | 0.934 ± 0.011 | 7.4 ± 1.8 | 0.022 ± 0.008 | 38 ± 8 | 0.035 ± 0.006 | 306 ± 132 | 0.008 ± 0.005 |
| 1 mM MgADP | 0.36 ± 0.01 | 0.988 ± 0.002 | 4.0 ± 1.0 | 0.005 ± 0.002 | 16.8 ± 2.6 | 0.007 ± 0.001 | np | np |
τCi and ai, closed times and their corresponding amplitudes in the distribution of closed times (i = 1–4); np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).