Table VI.

Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 1 mM MgADP

Solution τC1 aC1 τC2 aC2 τC3 aC3 τC4 aC4 
 ms  ms  ms  ms  
Control 0.34 ± 0.01 0.934 ± 0.011 7.4 ± 1.8 0.022 ± 0.008 38 ± 8 0.035 ± 0.006 306 ± 132 0.008 ± 0.005 
1 mM MgADP 0.36 ± 0.01 0.988 ± 0.002 4.0 ± 1.0 0.005 ± 0.002 16.8 ± 2.6 0.007 ± 0.001 np np 
Solution τC1 aC1 τC2 aC2 τC3 aC3 τC4 aC4 
 ms  ms  ms  ms  
Control 0.34 ± 0.01 0.934 ± 0.011 7.4 ± 1.8 0.022 ± 0.008 38 ± 8 0.035 ± 0.006 306 ± 132 0.008 ± 0.005 
1 mM MgADP 0.36 ± 0.01 0.988 ± 0.002 4.0 ± 1.0 0.005 ± 0.002 16.8 ± 2.6 0.007 ± 0.001 np np 

τCi and ai, closed times and their corresponding amplitudes in the distribution of closed times (i = 1–4); np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).

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