Table V.

Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 1 mM MgADP

Solution PO τO (ms) τO,COR τB1 aB1 τB2 aB2 τB3 aB2 τB 
  ms ms ms  ms  ms  ms 
Control 0.36 ± 0.03 2.4 ± 0.7 1.6 ± 0.1 53 ± 15 0.66 ± 0.06 11 ± 6 0.23 ± 0.06 0.9 ± 0.5 0.11 ± 0.01 37 ± 9 
1 mM MgADP 0.83 ± 0.01 2.7 ± 0.1 1.8 ± 0.1 246 ± 57 np np np np 246 ± 57 
Solution PO τO (ms) τO,COR τB1 aB1 τB2 aB2 τB3 aB2 τB 
  ms ms ms  ms  ms  ms 
Control 0.36 ± 0.03 2.4 ± 0.7 1.6 ± 0.1 53 ± 15 0.66 ± 0.06 11 ± 6 0.23 ± 0.06 0.9 ± 0.5 0.11 ± 0.01 37 ± 9 
1 mM MgADP 0.83 ± 0.01 2.7 ± 0.1 1.8 ± 0.1 246 ± 57 np np np np 246 ± 57 

PO, single-channel open probability; τO, mean open time; τO,COR, mean open time corrected for missed events (Proks et al., 2001); τBi and aBi, burst durations and their corresponding amplitudes in the distribution of burst lengths (i = 1–3); τB, mean burst duration; np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).

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