Table IV.

Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 10 mM MgATP

Solution τC1 aC1 τC2 aC2 τC3 aC3 τC4 aC4 
 ms  ms  ms  ms  
Control 0.33 ± 0.01 0.904 ± 0.002 4.4 ± 1.2 0.042 ± 0.006 33 ± 7 0.042 ± 0.006 166 ± 30 0.012 ± 0.005 
10 mM MgATP 0.34 ± 0.01 0.991 ± 0.002 2.9 ± 0.6 0.006 ± 0.002 16.7 ± 1.3 0.003 ± 0.001 np np 
Solution τC1 aC1 τC2 aC2 τC3 aC3 τC4 aC4 
 ms  ms  ms  ms  
Control 0.33 ± 0.01 0.904 ± 0.002 4.4 ± 1.2 0.042 ± 0.006 33 ± 7 0.042 ± 0.006 166 ± 30 0.012 ± 0.005 
10 mM MgATP 0.34 ± 0.01 0.991 ± 0.002 2.9 ± 0.6 0.006 ± 0.002 16.7 ± 1.3 0.003 ± 0.001 np np 

τCi and ai, closed times and their corresponding amplitudes in the distribution of closed times (i = 1–4); np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).

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