Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 10 mM MgATP
| Solution | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Control | 0.33 ± 0.01 | 0.904 ± 0.002 | 4.4 ± 1.2 | 0.042 ± 0.006 | 33 ± 7 | 0.042 ± 0.006 | 166 ± 30 | 0.012 ± 0.005 |
| 10 mM MgATP | 0.34 ± 0.01 | 0.991 ± 0.002 | 2.9 ± 0.6 | 0.006 ± 0.002 | 16.7 ± 1.3 | 0.003 ± 0.001 | np | np |
| Solution | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Control | 0.33 ± 0.01 | 0.904 ± 0.002 | 4.4 ± 1.2 | 0.042 ± 0.006 | 33 ± 7 | 0.042 ± 0.006 | 166 ± 30 | 0.012 ± 0.005 |
| 10 mM MgATP | 0.34 ± 0.01 | 0.991 ± 0.002 | 2.9 ± 0.6 | 0.006 ± 0.002 | 16.7 ± 1.3 | 0.003 ± 0.001 | np | np |
τCi and ai, closed times and their corresponding amplitudes in the distribution of closed times (i = 1–4); np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).