Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 10 mM MgATP
| Solution | PO | τO | τO,COR | τB1 | aB1 | τB2 | aB2 | τB3 | AB3 | τB |
| ms | ms | ms | ms | ms | ms | |||||
| Control | 0.34 ± 0.04 | 2.7 ± 0.3 | 1.8 ± 0.2 | 39 ± 4 | 0.57 ± 0.02 | 8.8 ± 2.4 | 0.28 ± 0.03 | 0.64 ± 0.18 | 0.15 ± 0.01 | 25 ± 2 |
| 10 mM MgATP | 0.83 ± 0.01 | 3.0 ± 0.3 | 2.0 ± 0.2 | 256 ± 50 | 1 | np | np | np | np | 256 ± 50 |
| Solution | PO | τO | τO,COR | τB1 | aB1 | τB2 | aB2 | τB3 | AB3 | τB |
| ms | ms | ms | ms | ms | ms | |||||
| Control | 0.34 ± 0.04 | 2.7 ± 0.3 | 1.8 ± 0.2 | 39 ± 4 | 0.57 ± 0.02 | 8.8 ± 2.4 | 0.28 ± 0.03 | 0.64 ± 0.18 | 0.15 ± 0.01 | 25 ± 2 |
| 10 mM MgATP | 0.83 ± 0.01 | 3.0 ± 0.3 | 2.0 ± 0.2 | 256 ± 50 | 1 | np | np | np | np | 256 ± 50 |
PO, single-channel open probability; τO, mean open time; τO,COR, mean open time corrected for missed events (Proks et al., 2001); τBi and aBi, burst durations and their corresponding amplitudes in the distribution of burst lengths (i = 1–3); τB, mean burst duration; np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).