Table III.

Single-channel parameters of Kir6.2-G334D/SUR1 channels in nucleotide-free solution and in the presence of 10 mM MgATP

Solution PO τO τO,COR τB1 aB1 τB2 aB2 τB3 AB3 τB 
  ms ms ms  ms  ms  ms 
Control 0.34 ± 0.04 2.7 ± 0.3 1.8 ± 0.2 39 ± 4 0.57 ± 0.02 8.8 ± 2.4 0.28 ± 0.03 0.64 ± 0.18 0.15 ± 0.01 25 ± 2 
10 mM MgATP 0.83 ± 0.01 3.0 ± 0.3 2.0 ± 0.2 256 ± 50 np np np np 256 ± 50 
Solution PO τO τO,COR τB1 aB1 τB2 aB2 τB3 AB3 τB 
  ms ms ms  ms  ms  ms 
Control 0.34 ± 0.04 2.7 ± 0.3 1.8 ± 0.2 39 ± 4 0.57 ± 0.02 8.8 ± 2.4 0.28 ± 0.03 0.64 ± 0.18 0.15 ± 0.01 25 ± 2 
10 mM MgATP 0.83 ± 0.01 3.0 ± 0.3 2.0 ± 0.2 256 ± 50 np np np np 256 ± 50 

PO, single-channel open probability; τO, mean open time; τO,COR, mean open time corrected for missed events (Proks et al., 2001); τBi and aBi, burst durations and their corresponding amplitudes in the distribution of burst lengths (i = 1–3); τB, mean burst duration; np, not present in the distribution. Data are expressed as mean ± SEM (n = 3 each).

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