Single-channel parameters of wild-type and Kir6.2-G334D/SUR1 channels in nucleotide-free solution
| Channel | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Wild-type | 0.40 ± 0.02 | 0.923 ± 0.014 | 15.2 ± 3.3 | 0.025 ± 0.003 | 114 ± 41 | 0.045 ± 0.014 | 253 ± 55 | 0.007 ± 0.002 |
| Kir6.2-G334D/SUR1 | 0.40 ± 0.02 | 0.943 ± 0.024 | 12.5 ± 2.4 | 0.019 ± 0.007 | 72 ± 34 | 0.026 ± 0.008 | 299 ± 88 | 0.010 ± 0.004 |
| Channel | τC1 | aC1 | τC2 | aC2 | τC3 | aC3 | τC4 | aC4 |
| ms | ms | ms | ms | |||||
| Wild-type | 0.40 ± 0.02 | 0.923 ± 0.014 | 15.2 ± 3.3 | 0.025 ± 0.003 | 114 ± 41 | 0.045 ± 0.014 | 253 ± 55 | 0.007 ± 0.002 |
| Kir6.2-G334D/SUR1 | 0.40 ± 0.02 | 0.943 ± 0.024 | 12.5 ± 2.4 | 0.019 ± 0.007 | 72 ± 34 | 0.026 ± 0.008 | 299 ± 88 | 0.010 ± 0.004 |
τCi, ai, closed times and their corresponding amplitudes in the distribution of closed times (i =1–4). Data are expressed as mean ± SEM (n = 3 each).