Table I. V 1/2 and P min of the P o c -V... | Rockefeller University Press

Table I.

V_1/2 and P_min of the P_o^c-V curves of various mutants

Channels/mutants	V_1/2	P_min	n
WT CLC-1	−45.9 ± 2.8^a	0.35 ± 0.02^a	15
V634A	−59.3 ± 0.8	0.64 ± 0.02	7
V634D	−34.0 ± 3.9	0.28 ± 0.02	7
V634F	−56.8 ± 2.0	0.40 ± 0.01	9
V634Y	−72.4 ± 1.8	0.50 ± 0.02	7
V634C	−44.4 ± 2.5	0.30 ± 0.01	7
V634S	−58.3 ± 0.9	0.42 ± 0.02	4
V634G	−47.6 ± 2.8	0.32 ± 0.01	7
V634W	−54.7 ± 2.6	0.45 ± 0.02	4
E865A	−68.5 ± 2.6	0.52 ± 0.01	4
E865D	−36.2 ± 2.5	0.24 ± 0.01	11
E865S	−43.7 ± 8.2	0.32 ± 0.01	3
V860A	−74.6 ± 1.3	0.67 ± 0.02	3
V860S	−54.9 ± 7.6	0.26 ± 0.02	4
V860Y	−37.5 ± 8.1	0.28 ± 0.01	4
V613A	−49.1 ± 3.4	0.37 ± 0.01	7
V613F	−43.9 ± 8.7	0.28 ± 0.02	3
V613G	88.2 ± 4.7	0.15 ± 0.01	5

Channels/mutants	V_1/2	P_min	n
WT CLC-1	−45.9 ± 2.8^a	0.35 ± 0.02^a	15
V634A	−59.3 ± 0.8	0.64 ± 0.02	7
V634D	−34.0 ± 3.9	0.28 ± 0.02	7
V634F	−56.8 ± 2.0	0.40 ± 0.01	9
V634Y	−72.4 ± 1.8	0.50 ± 0.02	7
V634C	−44.4 ± 2.5	0.30 ± 0.01	7
V634S	−58.3 ± 0.9	0.42 ± 0.02	4
V634G	−47.6 ± 2.8	0.32 ± 0.01	7
V634W	−54.7 ± 2.6	0.45 ± 0.02	4
E865A	−68.5 ± 2.6	0.52 ± 0.01	4
E865D	−36.2 ± 2.5	0.24 ± 0.01	11
E865S	−43.7 ± 8.2	0.32 ± 0.01	3
V860A	−74.6 ± 1.3	0.67 ± 0.02	3
V860S	−54.9 ± 7.6	0.26 ± 0.02	4
V860Y	−37.5 ± 8.1	0.28 ± 0.01	4
V613A	−49.1 ± 3.4	0.37 ± 0.01	7
V613F	−43.9 ± 8.7	0.28 ± 0.02	3
V613G	88.2 ± 4.7	0.15 ± 0.01	5

Error from curve fitting.