Table V.

Equilibrium constants for activation of α1β2γ2S and α3β3γ2S GABAA receptors using Scheme 1

 Kd = k–1/k+1 (μM) Φ = ϕ+1/ϕ−1 E1 = β1/α1 E2 = β2/α2 E3 = β3/α3 Σ = σ+1/σ−1 
α1β2γ2S 19.4 0.38 5.0 0.8 1.1 7.9 
α3β3γ2S 2.63 0.31 3.4 3.9 0.8 0.8 
 Kd = k–1/k+1 (μM) Φ = ϕ+1/ϕ−1 E1 = β1/α1 E2 = β2/α2 E3 = β3/α3 Σ = σ+1/σ−1 
α1β2γ2S 19.4 0.38 5.0 0.8 1.1 7.9 
α3β3γ2S 2.63 0.31 3.4 3.9 0.8 0.8 
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