Dwell-time distributions for α3β3γ2S GABAA receptors
| Shut | Open | ||||||
| 5 mM GABA (n = 16) | |||||||
| τ (ms) | 0.303 ± 0.014 | 1.28 ± 0.08 | 5.21 ± 0.42 | – | 0.628 ± 0.031 | 4.11 ± 0.80 | 10.8 ± 1.5 |
| Fraction | 0.72 ± 0.03 | 0.15 ± 0.02 | 0.13 ± 0.02 | – | 0.44 ± 0.03 | 0.39 ± 0.04 | 0.17 ± 0.04 |
| 200 µM GABA (n = 17) | |||||||
| τ (ms) | 0.255 ± 0.015 | 1.27 ± 0.18 | 5.51 ± 0.54 | – | 0.551 ± 0.038 | 2.80 ± 0.41 | 10.4 ± 0.17 |
| Fraction | 0.76 ± 0.06 | 0.18 ± 0.01 | 0.12 ± 0.02 | – | 0.43 ± 0.02 | 0.41 ± 0.02 | 0.17 ± 0.03 |
| 2 µM GABA (n = 7) | |||||||
| τ (ms) | 0.318 ± 0.020 | 1.59 ± 0.12 | 11.5 ± 1.8 | 38.3 ± 4.4 | 0.644 ± 0.069 | 1.73 ± 0.21 | 4.26 ± 0.14 |
| Fraction | 0.64 ± 0.02 | 0.14 ± 0.02 | 0.11 ± 0.02 | 0.11 ± 0.02 | 0.42 ± 0.04 | 0.44 ± 0.03 | 0.66 ± 0.02 |
| Shut | Open | ||||||
| 5 mM GABA (n = 16) | |||||||
| τ (ms) | 0.303 ± 0.014 | 1.28 ± 0.08 | 5.21 ± 0.42 | – | 0.628 ± 0.031 | 4.11 ± 0.80 | 10.8 ± 1.5 |
| Fraction | 0.72 ± 0.03 | 0.15 ± 0.02 | 0.13 ± 0.02 | – | 0.44 ± 0.03 | 0.39 ± 0.04 | 0.17 ± 0.04 |
| 200 µM GABA (n = 17) | |||||||
| τ (ms) | 0.255 ± 0.015 | 1.27 ± 0.18 | 5.51 ± 0.54 | – | 0.551 ± 0.038 | 2.80 ± 0.41 | 10.4 ± 0.17 |
| Fraction | 0.76 ± 0.06 | 0.18 ± 0.01 | 0.12 ± 0.02 | – | 0.43 ± 0.02 | 0.41 ± 0.02 | 0.17 ± 0.03 |
| 2 µM GABA (n = 7) | |||||||
| τ (ms) | 0.318 ± 0.020 | 1.59 ± 0.12 | 11.5 ± 1.8 | 38.3 ± 4.4 | 0.644 ± 0.069 | 1.73 ± 0.21 | 4.26 ± 0.14 |
| Fraction | 0.64 ± 0.02 | 0.14 ± 0.02 | 0.11 ± 0.02 | 0.11 ± 0.02 | 0.42 ± 0.04 | 0.44 ± 0.03 | 0.66 ± 0.02 |