Table III.

Dwell-time distributions for α3β3γ2S GABAA receptors

 Shut Open 
5 mM GABA (n = 16) 
τ (ms) 0.303 ± 0.014 1.28 ± 0.08 5.21 ± 0.42 – 0.628 ± 0.031 4.11 ± 0.80 10.8 ± 1.5 
Fraction 0.72 ± 0.03 0.15 ± 0.02 0.13 ± 0.02 – 0.44 ± 0.03 0.39 ± 0.04 0.17 ± 0.04 
200 µM GABA (n = 17) 
τ (ms) 0.255 ± 0.015 1.27 ± 0.18 5.51 ± 0.54 – 0.551 ± 0.038 2.80 ± 0.41 10.4 ± 0.17 
Fraction 0.76 ± 0.06 0.18 ± 0.01 0.12 ± 0.02 – 0.43 ± 0.02 0.41 ± 0.02 0.17 ± 0.03 
2 µM GABA (n = 7) 
τ (ms) 0.318 ± 0.020 1.59 ± 0.12 11.5 ± 1.8 38.3 ± 4.4 0.644 ± 0.069 1.73 ± 0.21 4.26 ± 0.14 
Fraction 0.64 ± 0.02 0.14 ± 0.02 0.11 ± 0.02 0.11 ± 0.02 0.42 ± 0.04 0.44 ± 0.03 0.66 ± 0.02 
 Shut Open 
5 mM GABA (n = 16) 
τ (ms) 0.303 ± 0.014 1.28 ± 0.08 5.21 ± 0.42 – 0.628 ± 0.031 4.11 ± 0.80 10.8 ± 1.5 
Fraction 0.72 ± 0.03 0.15 ± 0.02 0.13 ± 0.02 – 0.44 ± 0.03 0.39 ± 0.04 0.17 ± 0.04 
200 µM GABA (n = 17) 
τ (ms) 0.255 ± 0.015 1.27 ± 0.18 5.51 ± 0.54 – 0.551 ± 0.038 2.80 ± 0.41 10.4 ± 0.17 
Fraction 0.76 ± 0.06 0.18 ± 0.01 0.12 ± 0.02 – 0.43 ± 0.02 0.41 ± 0.02 0.17 ± 0.03 
2 µM GABA (n = 7) 
τ (ms) 0.318 ± 0.020 1.59 ± 0.12 11.5 ± 1.8 38.3 ± 4.4 0.644 ± 0.069 1.73 ± 0.21 4.26 ± 0.14 
Fraction 0.64 ± 0.02 0.14 ± 0.02 0.11 ± 0.02 0.11 ± 0.02 0.42 ± 0.04 0.44 ± 0.03 0.66 ± 0.02 

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