Dwell time distributions for α1β2γ2S GABAA receptors
| Shut | Open | ||||||
| 5 mM GABA (n = 7) | |||||||
| τ (ms) | 0.172 ± 0.014 | 0.809 ± 0.102 | 3.13 ± 0.37 | – | 0.477 ± 0.024 | 2.64 ± 0.14 | 7.44 ± 0.65 |
| Fraction | 0.65 ± 0.03 | 0.18 ± 0.03 | 0.17 ± 0.03 | – | 0.18 ± 0.02 | 0.61 ± 0.07 | 0.21 ± 0.05 |
| 200 µM GABA (n = 11) | |||||||
| τ (ms) | 0.216 ± 0.017 | 1.15 ± 0.09 | 5.9 ± 0.35 | – | 0.459 ± 0.063 | 2.75 ± 0.40 | 7.36 ± 0.88 |
| Fraction | 0.51 ± 0.04 | 0.17 ± 0.02 | 0.30 ± 0.03 | – | 0.23 ± 0.02 | 0.48 ± 0.04 | 0.28 ± 0.04 |
| 20 µM GABA (n = 4) | |||||||
| τ (ms) | 0.390 ± 0.067 | 2.35 ± 0.46 | 10.4 ± 1.7 | 32.7 ± 5.0 | 0.469 ± 0.091 | 1.81 ± 0.45 | 5.66 ± 1.06 |
| Fraction | 0.38 ± 0.06 | 0.15 ± 0.03 | 0.18 ± 0.02 | 0.32 ± 0.32 | 0.53 ± 0.03 | 0.26 ± 0.08 | 0.21 ± 0.06 |
| Shut | Open | ||||||
| 5 mM GABA (n = 7) | |||||||
| τ (ms) | 0.172 ± 0.014 | 0.809 ± 0.102 | 3.13 ± 0.37 | – | 0.477 ± 0.024 | 2.64 ± 0.14 | 7.44 ± 0.65 |
| Fraction | 0.65 ± 0.03 | 0.18 ± 0.03 | 0.17 ± 0.03 | – | 0.18 ± 0.02 | 0.61 ± 0.07 | 0.21 ± 0.05 |
| 200 µM GABA (n = 11) | |||||||
| τ (ms) | 0.216 ± 0.017 | 1.15 ± 0.09 | 5.9 ± 0.35 | – | 0.459 ± 0.063 | 2.75 ± 0.40 | 7.36 ± 0.88 |
| Fraction | 0.51 ± 0.04 | 0.17 ± 0.02 | 0.30 ± 0.03 | – | 0.23 ± 0.02 | 0.48 ± 0.04 | 0.28 ± 0.04 |
| 20 µM GABA (n = 4) | |||||||
| τ (ms) | 0.390 ± 0.067 | 2.35 ± 0.46 | 10.4 ± 1.7 | 32.7 ± 5.0 | 0.469 ± 0.091 | 1.81 ± 0.45 | 5.66 ± 1.06 |
| Fraction | 0.38 ± 0.06 | 0.15 ± 0.03 | 0.18 ± 0.02 | 0.32 ± 0.32 | 0.53 ± 0.03 | 0.26 ± 0.08 | 0.21 ± 0.06 |