Table II.

Dwell time distributions for α1β2γ2S GABAA receptors

 Shut Open 
 5 mM GABA (n = 7) 
τ (ms) 0.172 ± 0.014 0.809 ± 0.102 3.13 ± 0.37 – 0.477 ± 0.024 2.64 ± 0.14 7.44 ± 0.65 
Fraction 0.65 ± 0.03 0.18 ± 0.03 0.17 ± 0.03 – 0.18 ± 0.02 0.61 ± 0.07 0.21 ± 0.05 
 200 µM GABA (n = 11) 
τ (ms) 0.216 ± 0.017 1.15 ± 0.09 5.9 ± 0.35 – 0.459 ± 0.063 2.75 ± 0.40 7.36 ± 0.88 
Fraction 0.51 ± 0.04 0.17 ± 0.02 0.30 ± 0.03 – 0.23 ± 0.02 0.48 ± 0.04 0.28 ± 0.04 
 20 µM GABA (n = 4) 
τ (ms) 0.390 ± 0.067 2.35 ± 0.46 10.4 ± 1.7 32.7 ± 5.0 0.469 ± 0.091 1.81 ± 0.45 5.66 ± 1.06 
Fraction 0.38 ± 0.06 0.15 ± 0.03 0.18 ± 0.02 0.32 ± 0.32 0.53 ± 0.03 0.26 ± 0.08 0.21 ± 0.06 
 Shut Open 
 5 mM GABA (n = 7) 
τ (ms) 0.172 ± 0.014 0.809 ± 0.102 3.13 ± 0.37 – 0.477 ± 0.024 2.64 ± 0.14 7.44 ± 0.65 
Fraction 0.65 ± 0.03 0.18 ± 0.03 0.17 ± 0.03 – 0.18 ± 0.02 0.61 ± 0.07 0.21 ± 0.05 
 200 µM GABA (n = 11) 
τ (ms) 0.216 ± 0.017 1.15 ± 0.09 5.9 ± 0.35 – 0.459 ± 0.063 2.75 ± 0.40 7.36 ± 0.88 
Fraction 0.51 ± 0.04 0.17 ± 0.02 0.30 ± 0.03 – 0.23 ± 0.02 0.48 ± 0.04 0.28 ± 0.04 
 20 µM GABA (n = 4) 
τ (ms) 0.390 ± 0.067 2.35 ± 0.46 10.4 ± 1.7 32.7 ± 5.0 0.469 ± 0.091 1.81 ± 0.45 5.66 ± 1.06 
Fraction 0.38 ± 0.06 0.15 ± 0.03 0.18 ± 0.02 0.32 ± 0.32 0.53 ± 0.03 0.26 ± 0.08 0.21 ± 0.06 

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