Table I.

Pathological parameters of leukemic mice injected with transduced cells in vivo

Cells injected
Leukemia/mice
Disease latencya
Spleen weight
Liver weight

 

 

 
g
 
g
 
MIY control 0/10 No disease 0.035 ± 0.006 0.5 ± 0.09 
Ahi-1 8/8 70 ± 9.5 0.12 ± 0.04 1.1 ± 0.18 
BCR-ABL 8/8 41 ± 5.6 0.25 ± 0.05 1.6 ± 0.25 
Ahi-1 + BCR-ABL 8/8 26 ± 4 0.41 ± 0.08 2.1 ± 0.3 
Cells injected
Leukemia/mice
Disease latencya
Spleen weight
Liver weight

 

 

 
g
 
g
 
MIY control 0/10 No disease 0.035 ± 0.006 0.5 ± 0.09 
Ahi-1 8/8 70 ± 9.5 0.12 ± 0.04 1.1 ± 0.18 
BCR-ABL 8/8 41 ± 5.6 0.25 ± 0.05 1.6 ± 0.25 
Ahi-1 + BCR-ABL 8/8 26 ± 4 0.41 ± 0.08 2.1 ± 0.3 
a

Time (in days) to death caused by leukemia.

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