Table I.

Immunological data of patients

Ig levels (g/liter)

IgM
IgG
IgG1
IgG2
IgG3
IgG4
IgA
CD27+/CD19+ (%)a
P1b     (9 yr) 2.5b 3.5b ND ND ND ND <0.06b 
P2     (22 yr) 7.4 4.6 0.3 0.4 0.002 2.6 
P3     (9 yr) 0.8 8.7 ND ND ND ND 0.3 ND 
P3     (17 yr) 2.5 8.9 6.2 0.1 0.3 0.001 0.8 23 
Controls     (9 yr) 0.5–1.5 5.8–11.5     0.5–1.6 13–58 
Controls     (17–22 yr) 0.5–2.1 6.6–12.7 >4 >0.6 >0.2 >0.01 0.7–3.4 13–58 
Ig levels (g/liter)

IgM
IgG
IgG1
IgG2
IgG3
IgG4
IgA
CD27+/CD19+ (%)a
P1b     (9 yr) 2.5b 3.5b ND ND ND ND <0.06b 
P2     (22 yr) 7.4 4.6 0.3 0.4 0.002 2.6 
P3     (9 yr) 0.8 8.7 ND ND ND ND 0.3 ND 
P3     (17 yr) 2.5 8.9 6.2 0.1 0.3 0.001 0.8 23 
Controls     (9 yr) 0.5–1.5 5.8–11.5     0.5–1.6 13–58 
Controls     (17–22 yr) 0.5–2.1 6.6–12.7 >4 >0.6 >0.2 >0.01 0.7–3.4 13–58 

Bolded numbers indicate abnormal values. ND, not determined.

a

Gated on CD19+ B cells.

b

At age of immunodeficiency diagnosis before IgG substitution.

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