Table 1. Protein localization... | Rockefeller University Press

Table 1.

Protein localization information used for landmarks

Protein	Abbreviation	Number of cells	Protein sequence	UniProt	Localization	Reference
Cytochrome b5	Cytb5	Mu: 10,428	99-134	P00167	ER	D’Arrigo et al., 1993
		Mu: 4,452
Signal sequence of calreticulin, ER retention sequence (KDEL)	Calr-KDEL	Mu: 5,367	N/A	P27797	ER	Fliegel et al., 1989; Munro and Pelham, 1987
		Hu: 24,059
Bcl-2 interacting killer	Bik	Mu: 148,030	111-160	Q13323	ER	Germain et al., 2002
		Hu: 11,046
Ribosome-attached membrane protein 4	RAMP4	Hu: 2,269	1–166	Q9Y6X1	ER	Schröder et al., 1999
ER-Golgi intermediate compartment 53 kD	ERGIC53	Mu: 39,178	1–517	Q9D0F3	ERGIC	Scheel et al., 1997
		Hu: 73,059
β1,4-galactosyl-transferase	GalT	Mu: 60,260	1–81	P15291	Trans-Golgi	Roth and Berger, 1982
		Hu: 19,797
Golgin84	Golgin84	Mu: 147,916	674-731	Q8TBA6	Cis-Golgi	Diao et al., 2003
		Hu: 5,632
Golgi SNAP receptor complex member 2	Membrin	Hu: 19,288	1–212	O14653	Cis-Golgi	Hong, 2005
Monoamine oxidase A	MAO	Mu: 34,521	489-527	Q49A63	OMM	de Champlain et al., 1969
		Hu: 22,935
Cytochrome c oxidase, subunit VIII	CCO	Mu: 11,023	1–29	Q53XN1	IMM	Rizzuto et al., 1995
		Hu: 92,159
Phosphatidylserine synthase 1	PTDSS1	Mu: 137,908	1–473	Q99LH2	MAM, ER	Stone and Vance, 2000
Ras-related protein Rab3C	Rab3	Hu: 27,545	1–227	Q96E17	Secretory vesicles	Fischer von Mollard et al., 1994
Ras-related protein Rab5A	Rab5	Mu: 18,098	1–205	A0A024R2K1	Early endosome	Chavrier et al., 1990
		Hu: 27,137
Ras-related protein Rab7A	Rab7	Mu: 45,878	1–207	A0A158RFU6	Late endosome	Bucci et al., 2000
		Hu: 42,792
Ras-related protein Rab11B	Rab11B	Hu: 21,961	1–218	Q15907	Recycling endosome	Schlierf et al., 2000
Vesicle-associated membrane protein 2	VAMP2	Mu: 19,411	1–116	P63027	Secretory vesicles	Grote et al., 1995; Chen and Scheller, 2001
		Hu: 12,239
Vesicle-associated membrane protein 5	VAMP5	Mu: 43,352	1–116	O95183	Plasma membrane	Hong, 2005
		Hu: 39,946
Neuromodulin	Neuromodulin	Hu: 17,852	1–20	P17677	Plasma membrane	Skene and Virág, 1989
Vesicle-associated membrane protein 1, TMD deleted	ΔTMD-VAMP1	Mu: 19,074	1–99	P23763	Cytoplasm, nucleus	This study
Lamin A	Lamin A	Mu: 15,197	1–690	P02545	Nuclear envelope	Scaffidi and Misteli, 2008
Peroxisome targeting signal 1	PTS-1	Mu: 18,396	SKL	N/A	Peroxisome	Gould et al., 1989
		Hu: 27,712
Lysosomal-associated membrane protein 1	LAMP-1	Mu: 14,974	1–417	P11279	Lysosomes	Falcón-Pérez et al., 2005
		Hu: 17,162
Emerin	Emerin	Hu: 14,277	1–254	P50402	Nuclear envelope	Pfaff et al., 2016

Protein	Abbreviation	Number of cells	Protein sequence	UniProt	Localization	Reference
Cytochrome b5	Cytb5	Mu: 10,428	99-134	P00167	ER	D’Arrigo et al., 1993
		Mu: 4,452
Signal sequence of calreticulin, ER retention sequence (KDEL)	Calr-KDEL	Mu: 5,367	N/A	P27797	ER	Fliegel et al., 1989; Munro and Pelham, 1987
		Hu: 24,059
Bcl-2 interacting killer	Bik	Mu: 148,030	111-160	Q13323	ER	Germain et al., 2002
		Hu: 11,046
Ribosome-attached membrane protein 4	RAMP4	Hu: 2,269	1–166	Q9Y6X1	ER	Schröder et al., 1999
ER-Golgi intermediate compartment 53 kD	ERGIC53	Mu: 39,178	1–517	Q9D0F3	ERGIC	Scheel et al., 1997
		Hu: 73,059
β1,4-galactosyl-transferase	GalT	Mu: 60,260	1–81	P15291	Trans-Golgi	Roth and Berger, 1982
		Hu: 19,797
Golgin84	Golgin84	Mu: 147,916	674-731	Q8TBA6	Cis-Golgi	Diao et al., 2003
		Hu: 5,632
Golgi SNAP receptor complex member 2	Membrin	Hu: 19,288	1–212	O14653	Cis-Golgi	Hong, 2005
Monoamine oxidase A	MAO	Mu: 34,521	489-527	Q49A63	OMM	de Champlain et al., 1969
		Hu: 22,935
Cytochrome c oxidase, subunit VIII	CCO	Mu: 11,023	1–29	Q53XN1	IMM	Rizzuto et al., 1995
		Hu: 92,159
Phosphatidylserine synthase 1	PTDSS1	Mu: 137,908	1–473	Q99LH2	MAM, ER	Stone and Vance, 2000
Ras-related protein Rab3C	Rab3	Hu: 27,545	1–227	Q96E17	Secretory vesicles	Fischer von Mollard et al., 1994
Ras-related protein Rab5A	Rab5	Mu: 18,098	1–205	A0A024R2K1	Early endosome	Chavrier et al., 1990
		Hu: 27,137
Ras-related protein Rab7A	Rab7	Mu: 45,878	1–207	A0A158RFU6	Late endosome	Bucci et al., 2000
		Hu: 42,792
Ras-related protein Rab11B	Rab11B	Hu: 21,961	1–218	Q15907	Recycling endosome	Schlierf et al., 2000
Vesicle-associated membrane protein 2	VAMP2	Mu: 19,411	1–116	P63027	Secretory vesicles	Grote et al., 1995; Chen and Scheller, 2001
		Hu: 12,239
Vesicle-associated membrane protein 5	VAMP5	Mu: 43,352	1–116	O95183	Plasma membrane	Hong, 2005
		Hu: 39,946
Neuromodulin	Neuromodulin	Hu: 17,852	1–20	P17677	Plasma membrane	Skene and Virág, 1989
Vesicle-associated membrane protein 1, TMD deleted	ΔTMD-VAMP1	Mu: 19,074	1–99	P23763	Cytoplasm, nucleus	This study
Lamin A	Lamin A	Mu: 15,197	1–690	P02545	Nuclear envelope	Scaffidi and Misteli, 2008
Peroxisome targeting signal 1	PTS-1	Mu: 18,396	SKL	N/A	Peroxisome	Gould et al., 1989
		Hu: 27,712
Lysosomal-associated membrane protein 1	LAMP-1	Mu: 14,974	1–417	P11279	Lysosomes	Falcón-Pérez et al., 2005
		Hu: 17,162
Emerin	Emerin	Hu: 14,277	1–254	P50402	Nuclear envelope	Pfaff et al., 2016

The common name, abbreviation, and amino acid sequence used to construct the landmarks is indicated, with the UniProt ID for each of the coding regions. The reference provided includes the data for the assignment of localization and identification of the responsible targeting sequence. The number of cells refers to the number of cell images used in the analysis here. Hu, human image library; IMM, inner mitochondrial membrane; Mu, mouse image library; OMM, outer mitochondrial membrane.

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