Table 1.
Nuclear migration kinetics and shape change parameters that differ between hindbrain and retina
ParameterHindbrainRetinaP values
Starting positions (distance to the apical side, μm) 8.4 ± 3.9 6.7 ± 2.04 0.1266 
Variance of starting positions (μm215.01 4.16 0.0485 
Duration of apical migration (min) 13.3 ± 4.5 21.9 ± 7.9 0.0052 
Mean instantaneous velocity (μm/min) 0.63 ± 0.74 0.32 ± 0.77 <0.0001 
Directionality ratio 0.63 ± 0.06 0.36 ± 0.07 – 
Kurtosis of instantaneous velocity distribution 0.32 5.44 – 
Normalized nuclear aspect ratio (S) 0.00 ± 0.09 0.00 ± 0.10 0.7892 
Normalized nuclear aspect ratio (G2) 0.01 ± 0.16 0.17 ± 0.25 <0.0001 
Variance of the normalized nuclear aspect ratio (S) 0.008 0.001 0.02199 
Variance of the normalized nuclear aspect ratio (G2) 0.026 0.063 0.0001 
ParameterHindbrainRetinaP values
Starting positions (distance to the apical side, μm) 8.4 ± 3.9 6.7 ± 2.04 0.1266 
Variance of starting positions (μm215.01 4.16 0.0485 
Duration of apical migration (min) 13.3 ± 4.5 21.9 ± 7.9 0.0052 
Mean instantaneous velocity (μm/min) 0.63 ± 0.74 0.32 ± 0.77 <0.0001 
Directionality ratio 0.63 ± 0.06 0.36 ± 0.07 – 
Kurtosis of instantaneous velocity distribution 0.32 5.44 – 
Normalized nuclear aspect ratio (S) 0.00 ± 0.09 0.00 ± 0.10 0.7892 
Normalized nuclear aspect ratio (G2) 0.01 ± 0.16 0.17 ± 0.25 <0.0001 
Variance of the normalized nuclear aspect ratio (S) 0.008 0.001 0.02199 
Variance of the normalized nuclear aspect ratio (G2) 0.026 0.063 0.0001 

Values shown represent mean ± SD. P values were calculated using Levene’s test for the variance of starting positions of migration and variances of the normalized nuclear aspect ratio and Mann-Whitney test for starting positions of migration, duration of apical migration, instantaneous velocity, and normalized nuclear aspect ratios. –, not applicable.

or Create an Account

Close Modal
Close Modal